Description
A PI3K activator; increases phosphorylation of PI3K, mTOR, and GSK3β in HepG2 cells at 15 µM; prevents glucose-oxygen deprivation-induced decreases in viability of isolated rat hippocampal cells in an in vitro model of ischemia at 1 µM; has been used to expand isolated human umbilical cord blood HSCs ex vivo for up to 30 days in combination butyzamide, UM171, and PCL-PVAc-PEG