Biotinylated Recombinant SARS-CoV-2 S Protein RBD (carrier-free) 793906 from BioLegend

Product Specs
ItemBiotinylated Recombinant SARS-CoV-2 S Protein RBD (carrier-free)
CompanyBioLegend
Price $909.00Supplier Page View Company Product Page
Catalog Number793906
Size100 µg
ApplicationsBioassay
Conjugate/TagBiotinylated Recombinant
Format0.22 µm filtered protein solution is in PBS, pH 7.2
SpeciesSARS-CoV-2
Molecule NameSpike RBD
Concentration10 and 25 µg sizes are bottled at 200 µg/mL. 100 µg size and larger sizes are lot-specific and bottled at the concentration indicated on the vial. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) A new mRNA antigen vaccine induces potent B and T cell responses and in vivo protection against SARS-CoV-2npj VaccinesMarch 24, 2026Jing Wen, Jaesu Moon, Luca Tucciarone, Te-Hsuan Bu, Amanda Y. Sun, Robyn Miller, Julia Timis, Lujing Wu, Davey M. Smith, Sujan Shresta, et al.conjugated SARS-CoV-2 Spike RBD. The Biotinylated Recombinant SARS-CoV-2 S Protein RBD (Biolegend, 793904) was incubated with APC/Cyanine7 Streptavidin (Biolegend, 405208) at a 3:1 ratio for 1 h at 4 °C53. Cells

(2) Safety and pharmacokinetics of SARS-CoV-2 DNA-encoded monoclonal antibodies in healthy adults: a phase 1 trialNature medicineDecember 1, 2025Tebas P, Patel A, Agnes JT, Parzych EM, Baer A, Caturla M, Ghosh S, Purwar M, Bedanova N, Tsang C, et al.for 2 h at room temperature. Biotinylated SARS-CoV-2 RBD proteins representing wild-type (cat. no. 793906, BioLegend), Delta, BA.2 (cat. no. SPD-C82Eq, ACRO Biosystems) and BA.4/BA.5 (cat. no. SPD-C82EW, ACRO Biosystems

(3) Pediatric T cell and B cell responses to SARS-CoV-2 infectionJCI insightOctober 22, 2025Hills LB, Bhat N, Hurst JH, Myers A, Burke TW, McClain MT, Petzold E, Rotta AT, Turner NA, Grifoni A, et al.SARS-CoV-2–specific BMem, biotinylated full-length spike (Acro Biosystems, SPN-C82E9), RBD (BioLegend, 793904), or full-length nucleocapsid (Sino Biological, 40588-V27B-B) was tetramerized to fluorescently conjugated

(4) B cell maturation antigen (BCMA) is dispensable for the survival of long-lived plasma cellsNat CommunAugust 2, 2025Shannon R. Menzel, Edith Roth, Jens Wittner, Stefanie Brey, Leonie Weckwerth, Jana Thomas, Thomas H. Winkler, Wolfgang Schuh, Hans-Martin Jäck, Katharina Pracht, et al.1:400), CD38-PerCPCy5.5 (clone 90, BioLegend, Cat.: 102722, 1:100), and RBD-biotin (BioLegend, Cat.: 793904). The anti-BCMA antibody (clone 25C2)43 was produced and purified as described in ref. 10. For staining

(5) Vaccination with inactivated SARS-CoV-2 vaccine TURKOVAC induces durable humoral and cellular immune responses up to 8 monthsFrontiers in MedicineApril 28, 2025Seçil Yılmaz, Ahmet Eken, Zafer Sezer, Burcu Şen Bağcı, Serife Erdem, Medine Doğan Sarıkaya, Busra Kaplan, Ahmet Inal, Adnan Bayram, Gamze Kalın Unuvar, et al.cells were stained with a protein mix containing 200 ng of biotinylated Spike protein (BioLegend, #793906) and 50 ng of BV421 Streptavidin (BioLegend, #405226) and incubated at 4°C for 1 h. After washing with

(6) Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissuesImmunityDecember 1, 2024Julia Davis-Porada, Alex B. George, Nora Lam, Daniel P. Caron, Joshua I. Gray, Jenny Huang, Jennifer Hwu, Steven B. Wells, Rei Matsumoto, Masaru Kubota, et al.Biotinylated full-length SARS-CoV-2 S (R&D Systems; catalog no. AVI10549–050) and RBD (BioLegend; cat # 793904) were mixed with fluorescent streptavidin probes (STAR methods) (see fig S1 for gating) at a ~6:1 and

(7) Single-shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immunity in miceMolecular TherapyJuly 3, 2024Nicholas You Zhi Cheang, Kai Sen Tan, Peck Szee Tan, Kiren Purushotorma, Wee Chee Yap, Kirsteen McInnes Tullett, Benson Yen Leong Chua, Aileen Ying-Yan Yeoh, Caris Qi Hui Tan, Xinlei Qian, et al.B cell subsets Antigen-specific B cell subsets were detected using biotinylated SARS-CoV-2 RBD protein (793906; Biolegend) in combination with SAv-fluorophore conjugates as previously described.7 Briefly, biotinylated

(8) Ipsilateral immunization after a prior SARS-CoV-2 mRNA vaccination elicits superior B cell responses compared to contralateral immunizationCell reportsJanuary 23, 2024Jiang W, Maldeney AR, Yuan X, Richer MJ, Renshaw SE, Luo W.fluorochrome-conjugated antibodies against: SARS-CoV-2 Spike RBD tetramer (Alexa Fluor 647, BioLegend Cat: 793906, conjugated in our lab), SARS-CoV-2 Spike RBD tetramer (Alexa Fluor 785, BioLegend Cat: 793906, conjugated

(9) Tracking B cell responses to the SARS-CoV-2 mRNA-1273 vaccineCell reportsJuly 25, 2023Lopes de Assis F, Hoehn KB, Zhang X, Kardava L, Smith CD, El Merhebi O, Buckner CM, Trihemasava K, Wang W, Seamon CA, et al.SA1018 SARS-CoV-2 spike RBD APC tetramer TotalSeq-C0956/C0971,BioLegend and custom conjugation,Cat# 793906 SARS-CoV-2 spike S1 PE tetramer TotalSeq-C0961/0972,BioLegend and custom conjugation,Cat# 793806 Critical

(10) Vaccine subtype and dose interval determine immunogenicity of primary series COVID-19 vaccines in older peopleCell reports. MedicineSeptember 20, 2022Parry H, Bruton R, Ayodele R, Sylla P, McIlroy G, Logan N, Scott S, Nicol S, Verma K, Stephens C, et al.proteins","Chemicals, peptides, and recombinant proteins" ,, Biotinylated spike RBD protein,Biolegend,Cat # 793906 Dulbecco’s Phosphate Buffered Saline,Sigma,Cat # D8537 Fetal Bovine Serum,Sigma,Cat # F9665 GlutaMax

(11) Antibody and Memory B-Cell Immunity in a Heterogeneously SARS-CoV-2-Infected and -Vaccinated PopulationmBioAugust 30, 2022Bednarski E, Del Rio Estrada PM, DaSilva J, Boukadida C, Zhang F, Luna-Villalobos YA, Rodríguez-Rangel X, Pitén-Isidro E, Luna-García E, Díaz Rivera D, et al.647 (catalog no. 405237; BioLegend) at an ~6:1 molar ratio, and biotinylated RBD protein (catalog no. 793906; BioLegend) was mixed with streptavidin allophycocyanin (APC) Cy7 (catalog no. 554063; BD) at an ~4:1

(12) Antibody and memory B-cell immunity in a heterogeneously SARS-CoV-2 infected and vaccinated populationmedRxivAugust 25, 2022Eva Bednarski et al.647 (Biolegend, Cat No 405237) at ~6:1 molar ratio, and biotinylated RBD protein (Biolegend, Cat No 793906) mixed with streptavidin APC Cy7 (BD, Cat No 554063) at a ~4:1 molar ratio. Biotinylated proteins were

(13) SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to OmicronCellMarch 3, 2022Tarke A, Coelho CH, Zhang Z, Dan JM, Yu ED, Methot N, Bloom NI, Goodwin B, Phillips E, Mallal S, et al.(B.1.1.529) Spike Protein,AcroBiosystems,Cat# SPN-C82Ee Ancestral (WT) RBD Protein,BioLegend,Cat# 793906 Alpha (B.1.1.7) RBD Protein,AcroBiosystems,Cat# SPD-C82E6 Beta (B.1.351) RBD Protein,AcroBiosystems,Cat#

(14) Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infectionGut microbesJanuary 1, 2022Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M, et al.

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Biotinylated Recombinant SARS-CoV-2 S Protein RBD (carrier-free) from BioLegend

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Biotinylated Recombinant SARS-CoV-2 S Protein RBD (carrier-free) from BioLegend

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