Description
Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), also known as GZMB, is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity.1 Granzyme B may be a useful prognostic marker in early rheumatoid arthritis and may provide important clues to the pathogenesis of this disease.2