Description
IL-17F is a homodimeric protein that is a member of the IL17 family of cytokines produced by activated T-cells and monocytes.1 IL-17F is expressed by activated T cells and can stimulate production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover.2 IL-17F is an important regulator of inflammatory responses that function differently than IL-17 in immune responses and diseases.3