Description
SDF-1alpha (stromal cell-derived factor-1 alpha) is an alpha-chemokine for haematopoietic stem cells (HSC).1 SDF-1 alpha plays a role in two important processes of granule cell maturation - proliferation and migration - assisting in the achievement of appropriate cell number and position in the cerebellar cortex.2 SDF-1 alpha is also involved in the trafficking of hematopoietic progenitors and stem cells.3 It is expressed by liver cells and in liver diseases.4