Recombinant Human TNF-alpha (HEK293-expressed) Protein, CF 10291-TA-020 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human TNF-alpha (HEK293-expressed) Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $213.00Supplier Page View Company Product Page
Catalog Number10291-TA-020
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesTNFSF2, DIF, TNF-alpha, TNLG1F, TNFA
NCBI Full Gene Nametumor necrosis factor
Source/Expression SystemHEK293-derived Recombinant Human TNF-alpha (HEK293-expressed) Protein, CF
Molecule NameTNF-alpha
SpeciesHuman
Molecular WeightObserved: 14-18 kDa, under reducing conditions
Theoretical: 17 kDa
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
Conjugate/TagUnconjugated
ApplicationsBioactivity
Size20 ug (also 50 ug, 100 ug, 250 ug, 500 ug, 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Targeting APE1 endonuclease activity impairs metastasis and enhances genotoxic therapy response in pancreatic cancerResearch SquareDecember 16, 2025Eyram K. Kpenu, Mahmut Mijiti, Silpa Gampala, Jun Wan, Sheng Liu, Randall S. Wireman, Jacqueline Peil, Dana K. Mitchell, Sanya Haiaty, Rajesh Sardar, et al.was exchanged for regular growth media. For NF-κB-transfected cells, 20 ng/mL hTNFα (R&D Systems, Cat#10291-TA-020) was used for a 6h induction period, followed by a luciferase activity assay. Firefly and Renilla luciferase

(2) The CEMIP Hyaluronidase is Elevated in Oligodendrocyte Progenitor Cells and Inhibits Oligodendrocyte MaturationASN NeuroDecember 9, 2025Alec Peters, Kanon Yasuhara, Weiping Su, Steven Matsumoto, Peter Pham, Fatima Banine, Eliana Harris, Stephen A. Back, Larry S. Shermangrowth medium. The following day, cells were treated with either vehicle (PBS), or TNFα (R&D Systems, 10291-TA-020; 10 ng/mL) or IL6 (R&D Systems, 406-ML-005; 100 ng/ml). Growth factor and cytokine activity and concentration

(3) Differential immune- and apoptosis-related gene signatures in pancreatic alpha and beta cells contribute to their fate in type 1 diabetesbioRxiv : the preprint server for biologyJuly 31, 2025Yi X, Martin-Vazquez E, Jawurek S, Zimath PL, Oliveira JG, Costa-Junior JM, Ilegems E, Wesley JD, Title AC, Yesildag B, et al.

(4) NI-3201 Is a Bispecific Antibody Mediating PD-L1-Dependent CD28 Co-stimulation on T Cells for Enhanced Tumor ControlCancer immunology researchMarch 4, 2025Majocchi S, Lloveras P, Nouveau L, Legrand M, Viandier A, Malinge P, Charreton M, Raymond C, Pace EA, Millard BL, et al.

(5) TBK1 Targeting Is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor SpheroidsCancer immunology researchFebruary 3, 2025Sun Y, Maggs L, Panda A, Wright SJ, Cicerchia AM, Jenney A, Perricone MD, Mills CE, Cattaneo G, Ventin M, et al.

(6) Polymeric immunoglobulin receptor promotes Th2 immune response in the liver by increasing cholangiocytes derived IL-33: a diagnostic and therapeutic biomarker of biliary atresiaEBioMedicineOctober 1, 2024Li Y, Li TY, Qiao Q, Zhang MT, Tong MX, Xu LF, Zhang ZB.

(7) TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial PhenotypeInternational journal of molecular sciencesAugust 9, 2024Hayderi A, Zegeye MM, Meydan S, Sirsjö A, Kumawat AK, Ljungberg LU.

(8) In vitro and In vivo evidence demonstrating chronic absence of Ref-1 Cysteine 65 impacts Ref-1 folding configuration, redox signaling, proliferation and metastasis in pancreatic cancerRedox biologyFebruary 1, 2024Mijit M, Kpenu E, Chowdhury NN, Gampala S, Wireman R, Liu S, Babb O, Georgiadis MM, Wan J, Fishel ML, et al.another parallel set in normoxia for 24h. For NF-κB transfected cells, 20 ng/mL hTNFα (R&D Systems, Cat#10291-TA-020) was used for a 6h induction before assaying for luciferase activity. Firefly and Renilla luciferase

(9) Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertensionNature communicationsJanuary 6, 2024Ulrich A, Wu Y, Draisma H, Wharton J, Swietlik EM, Cebola I, Vasilaki E, Balkhiyarova Z, Jarvelin MR, Auvinen J, et al.

(10) Cytokine-Induced iNOS in A549 Alveolar Epithelial Cells: A Potential Role in COVID-19 Lung PathologyBiomedicinesOctober 3, 2023Barilli A, Recchia Luciani G, Visigalli R, Sala R, Soli M, Dall'Asta V, Rotoli BM.

(11) An integrated organoid omics map extends modeling potential of kidney diseaseNature communicationsAugust 14, 2023Lassé M, El Saghir J, Berthier CC, Eddy S, Fischer M, Laufer SD, Kylies D, Hutzfeldt A, Bonin LL, Dumoulin B, et al.

(12) GPR84 regulates pulmonary inflammation by modulating neutrophil functionsActa pharmacologica SinicaAugust 1, 2023Wang SW, Zhang Q, Lu D, Fang YC, Yan XC, Chen J, Xia ZK, Yuan QT, Chen LH, Zhang YM, et al.

(13) Therapy-induced APOBEC3A drives evolution of persistent cancer cellsNatureAugust 1, 2023Isozaki H, Sakhtemani R, Abbasi A, Nikpour N, Stanzione M, Oh S, Langenbucher A, Monroe S, Su W, Cabanos HF, et al.

(14) Lactobacillus rhamnosus postbiotic-induced immunomodulation as safer alternative to the use of live bacteriaCytokineOctober 1, 2021Salva S, Tiscornia I, Gutiérrez F, Alvarez S, Bollati-Fogolín M.

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TNF-alpha (HEK293-expressed) Protein

TNF-alpha (HEK293-expressed) Protein

TNF-alpha (HEK293-expressed) Protein

TNF-alpha (HEK293-expressed) Protein

TNF-alpha (HEK293-expressed) Protein

Recombinant Human TNF-alpha (HEK293-expressed) Protein, CF from R&D Systems, a Bio-Techne Brand

Description

R&D Systems, a Bio-Techne Brand

Citations (14)

Reviews

Recombinant Human TNF-alpha (HEK293-expressed) Protein, CF from R&D Systems, a Bio-Techne Brand

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