SARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein 40592-VNAH from Sino Biological, Inc.

Product Specs
ItemSARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein
CompanySino Biological, Inc.
Price $448.00Supplier Page View Company Product Page
Catalog Number40592-VNAH
TypeRecombinant protein
Molecule NameSpike
SpeciesSARS-CoV-2
FormatLyophilized from sterile PBS, pH 7.4
Conjugate/TagUnconjugated
Source/Expression SystemHEK293 Cells
Molecular WeightThe recombinant SARS-CoV-2 (2019-nCoV) Spike Protein (RBD) consists of 223 amino acids and predicts a molecular mass of 25.1 kDa
Purity> 90 % as determined by SDS-PAGE
ActivityMeasured by its binding ability in a functional ELISA. Immobilized S3-2019-nCov-RBD（40592-VNAH) at 2 µg/mL (100 µL/well) can bind ACE2 Protein, Human, Recombinant (mFc Tag) (10108-H05H), the EC50 of ACE2 Protein, Human, Recombinant (mFc Tag) (10108-H05H) is 20-80 ng/mL
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Generation of antigen-specific paired-chain antibodies using large language modelsCellNovember 1, 2025Perry T. Wasdin, Nicole V. Johnson, Alexis K. Janke, Sofia Held, Toma M. Marinov, Gwen Jordaan, Rebecca A. Gillespie, Léna Vandenabeele, Fani Pantouli, Olivia C. Powers, et al.experiments, SARS-CoV-2 Index S RBD (2019-nCoV) was purchased from Sino Biological catalog number (40592-VNAH) while SARS-CoV-2 S Hexapro Index strain, SARS-CoV-2 S XBB.1, and SARS-CoV-1 S were expressed in Expi293F cells

(2) Simultaneous and sensitive detection of Mycobacterium tuberculosis and SARS-CoV-2 antigens employing an electrochemical impedance spectroscopy aptasensorFrontiers in Bioengineering and BiotechnologyOctober 31, 2025Zhazira Zhumabekova, Timur Elebessov, Tri Thanh Pham, Damira KanayevaEurogentec (Belgium), and the sequences are listed in Table 1. The SARS-CoV-2 S glycoprotein (cat. no. 40592-VNAH), monkey pox virus (MPXV) A29 protein (cat. no. 40891-V08E), and Middle East respiratory syndrome-related coronavirus

(3) Validation of new equipment for SARS-CoV-2 diagnosis in Ecuador: Detection of the virus and antibodies generated by disease and vaccines with one POC devicePloS oneJanuary 1, 2025Villota SD, Veloz-Villavicencio E, Garcia-Iturralde S, Arévalo JV, Lu S, Jaenes K, Guo Y, Cicek S, Colwill K, Gingras AC, et al.comparison to the control batch to obtain similar performance) spike-RBD antigen (Sino Biological, Cat. No. 40592-VNAH) or 0.5 µg/mL N antigen (Sino Biological, Cat. No. 40588-V07E) diluted in sterile 1X PBS. Plates were

(4) Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral familiesPLOS PathogensSeptember 18, 2024Matthew J. Vukovich, Andrea R. Shiakolas, Jared Lindenberger, Robert A. Richardson, Lindsay E. Bass, Maggie Barr, Yanshun Liu, Eden P. Go, Chan Soo Park, Aaron J. May, et al.domain, amino acids 708S-1207E. SARS-CoV-2 spike RBD subunit was obtained from SinoBiological (Cat:40592-VNAH) and was expressed in HEK293 cells. The RBD subunit consisted of amino acids Arg319-Phe541. SARS-CoV-2

(5) Rapid detection of carcinoembryonic antigen by means of an electrochemical aptasensoriScienceMay 17, 2024Nigara Yunussova, Meruyert Tilegen, Tri Thanh Pham, Damira KanayevaSRP3096 HSA,Sigma-Aldrich,Cat# SRP6182-1MG SARS-CoV-2 (2019-nCoV) Spike RBD recombinant,Sino Biological,Cat# 40592-VNAH ,, Oligonucleotides,Oligonucleotides,Oligonucleotides ,, CEA aptamer (6): HS-(CH6)6-OP(O)2O-(CH2CH2O)6-5′-TTTTT-GCCAGCGAGTTTTGACCGTTTTTCTCTCTTTTCCGCCTA-3′,Previously

(6) SARS-CoV-2-Specific Immune Responses in Vaccination and Infection during the Pandemic in 2020-2022VirusesMarch 13, 2024Wakana Inoue, Yuta Kimura, Shion Okamoto, Takuto Nogimori, Akane Sakaguchi-Mikami, Takuya Yamamoto, Yasuko Tsunetsugu-Yokota(RBD) derived from SARS-CoV-2 Wuhan-1 spike antigen was obtained commercially (Sino Biological, cat. 40592-VNAH). We used these antigens for the ELISA test. For the in vitro stimulation of PBMC, a codon-humanized

(7) Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1Structure (London, England : 1993)March 7, 2024Ozawa T, Ikeda Y, Chen L, Suzuki R, Hoshino A, Noguchi A, Kita S, Anraku Y, Igarashi E, Saga Y, et al.

(8) Salivary IgA and vimentin differentiate in vitro SARS-CoV-2 infection: A study of 290 convalescent COVID-19 patientsMucosal ImmunologyFebruary 1, 2024Samuel Ellis, Rosie Way, Miranda Nel, Alice Burleigh, Ivan Doykov, Japhette Kembou-Ringert, Maximillian Woodall, Tereza Masonou, Katie-Marie Case, Arturo Torres Ortez, et al.Institute, UK) and SARS-CoV-2 spike receptor-binding domain (RBD) (Sinobiological Eschborn, Germany 40592-VNAH-SIB). We used 96-well ELISA plates (Nunc Maxisorp) coated with 50 µL antigen solution at 2 µg/ml in

(9) Safety and immunogenicity of SARS-CoV-2 self-amplifying RNA vaccine expressing an anchored RBD: A randomized, observer-blind phase 1 studyCell reports. MedicineAugust 15, 2023Akahata W, Sekida T, Nogimori T, Ode H, Tamura T, Kono K, Kazami Y, Washizaki A, Masuta Y, Suzuki R, et al.,Thermo Fisher Scientific,cat# L23105 Cytofix/Cytoperm kit,BD Biosciences,cat# 554714 RBD protein,SinoBiological,cat# 40592-VNAH Peroxidase Substrate Solution B,KPL,cat# 50-65-02 TMB Peroxidase Substrate,KPL,cat# 50-76-02 HRP-conjugated streptavidin

(10) Repurposing the oncolytic virus VSV∆51M as a COVID-19 vaccineFrontiers in Bioengineering and BiotechnologyJuly 17, 2023Almohanad A. Alkayyal, Manar Darwish, Reham Ajina, Saleh Y. Alabbas, Mohammed A. Alotaibi, Abeer Alsofyani, Maha Bokhamseen, Maumonah Hakami, Omar A. Albaradie, Abdulaziz M. Moglan, et al.coated with 1ug/mL SARS-Cov-2 Spike RBD recombinant protein (Sino Biological Inc., Beijing, China, cat# 40592-VNAH) overnight at 4°C. Plates were then washed with PBST, Phosphate Buffer Saline with 0.05% tween-20, (SIGMA)

(11) Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 InterfaceInternational Journal of Molecular SciencesMay 15, 2023Kelly Bugatti, Andrea Sartori, Lucia Battistini, Crescenzo Coppa, Emiel Vanhulle, Sam Noppen, Becky Provinciael, Lieve Naesens, Annelies Stevaert, Alessandro Contini, et al.peptidomimetics to the RBD of the wild-type Wuhan-Hu-1 SARS-CoV-2 spike protein (2019-nCoV spike RBD, cat n° 40592-VNAH, SinoBiological, Beijing, China). The RBD was immobilized on a CM5 sensor chip using standard amine

(12) Establishment of angiotensin-converting enzyme 2 and cluster of differentiation 147 dual target cell membrane chromatography based on SNAP-tag technology for screening anti severe acute respiratory syndrome coronavirus 2 active componentsJournal of chromatography. AMarch 29, 2023Wang H, Jia Q, Feng J, Miao C, Ding Y, Liu S, Feng C, Lv Y, Huang J, Han S.columns ACE2-ST/CMC and CD147-ST/CMC columns (10 × 2 mm) were prepared as previously prepared. SARS-CoV-2 S protein (40592-VNAH, Sino Biological) was dissolved in Watson's water at a concentration of 200 ug/mL as a reference stock

(13) SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virusFrontiers in ImmunologyJanuary 31, 2023Almohanad A. Alkayyal, Reham Ajina, Marco Cacciabue, Aaesha A. Alkayyal, Nizar H. Saeedi, Taofik Hussain Alshehry, Feras Kaboha, Mohammed A. Alotaibi, Nada Zaidan, Khalid Shah, et al.ascending concentrations of the recombinant RBD protein (Sino Biological Inc., Beijing, China, cat# 40592-VNAH) as indicated in ( Figure 3D ) and infected with VSV-Δ51 at 0.01 MOI. When needed, the neutralizing

(14) Antibody response in children with multisystem inflammatory syndrome related to COVID-19 (MIS-C) compared to children with uncomplicated COVID-19Frontiers in immunologyJanuary 1, 2023Thiriard A, Meyer B, Eberhardt CS, Loevy N, Grazioli S, Adouan W, Fontannaz P, Marechal F, L'Huillier AG, Siegrist CA, et al.(EPFL, protein production facility), receptor-binding-domain of the spike protein (RBD) (SinoBiological #40592-VNAH), sub-unit S1 (SinoBiological #40591-V08H), and the sub-unit S2 (SinoBiological #40590-V08B) and nucleocapside

(15) Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challengeFrontiers in immunologyJanuary 1, 2023Gary EN, Tursi NJ, Warner BM, Cuismano G, Connors J, Parzych EM, Griffin BD, Bell MR, Ali AR, Frase D, et al.control of binding to RBD (Purified Wuhan recombinant Spike RBD, Sino Biological, BDA, Beijing, RBD-His 40592-VNAH, FC2), S1 (S1-His 40150-V08B1), and S2 (S2-mfc 40590-V05B). S2-His 40590-V05B expressed in insect cells

(16) Younger Children Develop Higher Effector Antibody Responses to SARS-CoV-2 InfectionOpen Forum Infectious DiseasesNovember 30, 2022Lisa Tomasi, Anais Thiriard, Leo Heyndrickx, Daphnée Georges, Sigi Van den Wijngaert, Véronique Olislagers, Shilpee Sharma, André Matagne, Margaret E Ackerman, Kevin K Ariën, et al.University of Geneva, Switzerland), receptor-binding domain of the spike protein (RBD; SinoBiological #40592-VNAH), subunit S1 (SinoBiological #40591-V08H), and subunit S2 (SinoBiological #40590-V08B). The following

(17) Structural and biochemical characteristics of mRNA nanoparticles determine anti–SARS-CoV-2 humoral and cellular immune responsesScience AdvancesNovember 25, 2022Yingying Shi, Jiaxin Huang, Yu Liu, Jing Liu, Xuemeng Guo, Jianhua Li, Liming Gong, Xin Zhou, Guofeng Cheng, Yunqing Qiu, et al.were incubated with/without SARS-CoV-2 (2019-nCoV) Spike RBD recombinant protein (5 μg/ml; catalog no. 40592-VNAH, Sino Biological, Beijing, China) in complete 1640 medium supplemented with mouse recombinant IL-2 (10

(18) Sensitive Detection of SARS-CoV-2 Variants Using an Electrochemical Impedance Spectroscopy Based AptasensorInternational journal of molecular sciencesOctober 28, 2022Kurmangali A, Dukenbayev K, Kanayeva D.Eurogentec (Seraing, Belgium). SARS-CoV-2 (2019-nCoV) Spike RBD recombinant protein (25.1 kDa; cat. no. 40592-VNAH; YP_009724390; Arg319-Phe541) and MERS-CoV Spike/RBD protein fragment (aa 367-606, His Tag; 27.7 kDa;

(19) A microarray patch SARS-CoV-2 vaccine induces sustained antibody responses and polyfunctional cellular immunityiScienceOctober 21, 2022Balmert SC, Ghozloujeh ZG, Carey CD, Williams LH, Zhang J, Shahi P, Amer M, Sumpter TL, Erdos G, Korkmaz E, et al.recombinant SARS-CoV-2 S1 spike protein (Sino Biological #40591-V08H) or spike RBD protein (Sino Biological #40592-VNAH) in PBS by overnight incubation at 4°C. Plates were washed three times with 0.05% Tween 20 in PBS and

(20) Enzyme linked oligonucleotide assay for the sensitive detection of SARS-CoV-2 variantsFrontiers in Cellular and Infection MicrobiologySeptember 29, 2022Michael Shola David, Damira Kanayevausing BioRender.com (GC2408DSS7). Proteins SARS-CoV-2 (2019-nCoV) spike RBD recombinant protein (40592-VNAH), SARS-CoV-2 spike antibody chimeric MAb (40150-D005), MERS-CoV recombinant spike protein (40071-V08B1),

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SARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein

SARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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SARS-CoV-2 (2019-nCoV) Spike RBD Recombinant Protein from Sino Biological, Inc.

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