Caspase-3/7 Inhibitor I 27741-2 from BPS Bioscience, Inc. | Biocompare.com

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Caspase-3/7 Inhibitor I

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Caspase-3/7 Inhibitor I

Description

A potent, cell-permeable, and specific, reversible inhibitor of caspase-3 and caspase-7

Product Specs
ItemCaspase-3/7 Inhibitor I
CompanyBPS Bioscience, Inc.
Price $455.00Supplier Page View Company Product Page
Catalog Number27741-2
Size10 mg
ActivityCaspase-3/7 inbibitor I is a potent, reversible, isatin sulfonamide-based inhibitor of caspase-3 (Ki = 60 nM, IC50= 120 nM) and caspase-7 (Ki = 170 nM). It is a weaker inhibitor of caspase-9 (Ki = 3.1 µM). It Has only a trivial effect (Ki(app) >25 µM) on the activities of caspase-1, caspase-2, caspase-4, caspase-6, and caspase-8. It has been shown to inhibit apoptosis in camptothecin treated Jurkat cells (IC50 ~50 µM). Also it has been reported to inhibit apoptosis in chondrocytes (44% inhibition at 10 µM and 98% inhibition at 50 µM)
Molecular Weight324.4 Da
FormulaC₁₄H₁₆N₂O₅S
TypeInhibitor
TargetCaspase3, 7
FormatA crystalline solid

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BPS Bioscience, Inc.

BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

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