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4-iodo-SAHA
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4-iodo-SAHA
4-iodo-SAHA
4-iodo-SAHA
4-iodo-SAHA from BPS Bioscience, Inc.
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(1)
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BPS Bioscience, Inc. for
4-iodo-SAHA
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Description
4-iodo-SAHA is a hydrophobic derivative of SAHA, a class I and class II histone deacetylase (HDAC) inhibitor. Similar to SAHA, it demonstrates > 60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay at 1 µM
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Product Specs
Item
4-iodo-SAHA
Company
BPS Bioscience, Inc.
Price
$170.00
Supplier Page
View Company Product Page
Catalog Number
27205
Size
50 mg
Activity
4-iodo-SAHA inhibits SKBR3 breast-derived and HT29 colon-derived cell line proliferation with EC50 values comparable to that of SAHA (1.1 µM and 0.95 µM versus 2.1 µM and 2 µM, respectively). It has 10 times the inhibition strength of U937 leukemia cell proliferation in comparison to SAHA (0.12 µM versus 1.2 µM, respectively)
Purity
≥98% by HPLC
Molecular Weight
390.2 Da
Formula
C
14
H
19
IN
2
O
3
Type
Inhibitor
Format
A crystalline solid
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BPS Bioscience, Inc.
6405 Mira Mesa Blvd
Suite 100
San Diego
,
CA
92121
United States
Phone
: 858-202-1401
Email: sales-team@bpsbioscience.com
Company Profile
Website:
https://bpsbioscience.com/
Citations (1)
(1)
Mutagenicity and DNA Damage of Bisphenol a and its Structural Analogues in Hepg2 Cells
Archives of Industrial Hygiene and Toxicology
July 4, 2013
Anja Fic, Bojana Žegura, Marija Sollner Dolenc, Metka Filipič, Lucija Peterlin Mašič
(DMBPS, 97 % pure; CAS # 1634697-7), [sulphonylbis(benzene-4,1-diyloxy)]diethanol (BP-1, 95 % pure; CAS #
27205
-03-4), 4,4’sulphanediyldiphenol (BP-2, 99 % pure; CAS # 266463-3), William’s medium E, ampicillin, 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
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4-iodo-SAHA from BPS Bioscience, Inc.
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$170.00
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