EPZ004777 27622 from BPS Bioscience, Inc. | Biocompare.com

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EPZ004777

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BPS Bioscience, Inc. for
EPZ004777

Description

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 400 pM. EPZ004777 selectively kills a variety of MLL-rearranged leukemia cells, including an MLL-AF4 leukemia cell line MV4-11 and an MLL-AF9 leukemia cell line MOLM13

Product Specs
ItemEPZ004777
CompanyBPS Bioscience, Inc.
Price $205.00Supplier Page View Company Product Page
Catalog Number27622
Size5 mg
ActivityEPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 400 pM. EPZ004777 also exhibits anti-proliferative activity against both MLL-rearranged and non-rearranged human leukemia cell lines, including RS4;11 (IC50: 6.47 µM), SEM (IC50: 1.72 µM), MV4-11 (IC50: 0.17 µM), THP-1 (IC50: 3.36 µM), MOLM-13 (IC50: 0.72 µM), KOPN-8 (IC50: 0.62 µM), REH (IC50: 13.9 µM), Kasumi-1 (IC50: 32.99 µM) and 697 (IC50: 36.57 µM)
Molecular Weight539.7 Da
FormulaC₂₈H₄₁N₇O₄
TypeMethyltransferase Inhibitor
TargetDot1L

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BPS Bioscience, Inc.

BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

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