Apremilast (CC-10004) 27735-1 from BPS Bioscience, Inc. | Biocompare.com

Supplier Images

Apremilast (CC-10004)

Be the first to write a review!

Supplier Page from
BPS Bioscience, Inc. for
Apremilast (CC-10004)

Description

Apremilast, also known as CC-10004, is a novel and potent small-molecule inhibitor of phosphodiesterase 4 (PDE4), a key enzyme involved in cyclic adenosine monophosphate (cAMP) degradation and cytokine production of inflammatory cells

Product Specs
ItemApremilast (CC-10004)
CompanyBPS Bioscience, Inc.
Price $260.00Supplier Page View Company Product Page
Catalog Number27735-1
Size5 mg
ActivityApremilast binds to the catalytic site of PDE4, with values of inhibition constant IC50 and affinity constant Kiof 0.074 µM and 68 nM respectively, consequently leading to the degradation of cAMP. Apremilast exhibits anti-inflammatory activities against inflammatory disease in animal models as well as human chronic inflammatory diseases (such as psoriasis and psoriatic arthritis) by blocking the synthesis of a range of pro-flammatory cytokines and chemokines, including tumor necrosis factor alpha, interleukin 23, CXCL9 and CXCL10
Molecular Weight460.5 Da
FormulaC₂₂H₂₄N₂O₇S
TypePDE Inhibitor
TargetPDE4

Add to Compare List

BPS Bioscience, Inc.

BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

Be the First to Write a Review!