Description
The echinoglycoproteins of coronaviruses contain projections that bind only to certain receptors on host cells. The known receptors for binding S1 are ACE2, angiotensin converting enzyme 2, DPP4, dipeptidin-4, APN, aminopeptidase N, CEACAM, oncogenic antigen associated cell adhesion molecule 1, Sia, sialic acid, o-ac Sia, o-acetylated sialic acid. Peaks are critical for host specificity and viral infectivity