Description
CSF2RA, also known as granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform g, is a well-known hemopoietic growth factor that is used in the clinic to correct neutropaenia, usually as a result of chemotherapy. It is a key regulatory molecule causative of this aortopathy, and modulation of this cytokine might be an exploitable treatment strategy for the condition. It transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Recombinant human CSF2RA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques