Description
Introduction: LRP4 encodes a part of the low-density lipoprotein receptor-related protein family, which comprises of many evolutionarily conserved transmembrane proteins. LRP4 mediates SOST-dependent inhibition of bone formation. LRP4 takes part in the formation and the maintenance of the neuromuscular junction which is the synapse between skeletal muscle and motor neuron. LRP4 plays a role as a specific facilitator of SOST-mediated inhibition of Wnt signaling.
Description: LRP4 Human Recombinant is a single, glycosylated polypeptide chain containing 1719 amino acids (21-1725a.a) and having a molecular mass of 191.6kDa (calculated). LRP4 is fused to a 14 a.a His tag (2 a.a on N-terminal and 12 a.a on C-terminal)