Description
Description: GCGR Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain (a.a 27-142) containing 125 amino acids including a 9 a.a C-terminal His tag. The total molecular mass is 14.9kDa (calculated).
Introduction: Glucagon receptor is part of the glucagon receptor family which also contains GLP-1, GLP-2, GHRH and GIP receptors. GCGR regulates blood glucose levels and is mainly expressed in the pancreas, liver and kidneys. Mutations in GCGR are a cause of non-insulin-dependent diabetes mellitus.