Description
Introduction: Fas apoptotic inhibitory molecule 3 or FCMR takes part in processes occurring within the immune system. The FCMR is protecting cells from apoptosis that is induced by FADD, FAS and TNF alpha proteins, without over expressing inhibitors of apoptosis such as BCLXL or BCL2. FCMR activates an inhibitory pathway that inhibits CASP8 activation, instead of blocking apoptotic signals downstream.
Description: FCMR Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 18-250) containing 243 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 27.2kDa (calculated)