Human IL-6R / CD126 Protein (ECD, Fc Tag) 10398-H02H from Sino Biological, Inc.

Product Specs
ItemHuman IL-6R / CD126 Protein (ECD, Fc Tag)
CompanySino Biological, Inc.
Price $348.00Supplier Page View Company Product Page
Catalog Number10398-H02H
Activity1.Measured by its ability to enhance the activity of IL6 on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 30-125 ng/mL in the presence of 100 ng/mL of recombinant human IL6. 2.Loaded Recombinant Human IL-6R Protein, hFc Tag (Cat. No. 10398-H02H) on ProA Biosensor, can bind Recombinant Human IL-6 Protein, no Tag (Cat. No. 10395-HNAE) with an affinity constant of 0.51µM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Immobilized Recombinant Human IL6 / Interleukin-6 Protein (Cat: 10395-HNAE) at 2µg/mL (100µL/well) can bind Recombinant Human IL-6R / CD126 Protein (ECD, Fc Tag) (Cat: 10398-H02H), the EC50 is 5-15 ng/mL. 4.Recombinant Human IL-6R / CD126 Protein (ECD, Fc Tag) (Cat: 10398-H02H) captured on Protein A chip, can bind Recombinant Human IL-6 protein (Cat: 10395-HNAH) with an affinity constant of 65.470 nM as determined in an SPR assay (Biacore T200) (Routinely tested)
Conjugate/TagC-human IgG1-Fc
FormatLyophilized from sterile PBS, pH 7.4
Purity> 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human IL6R consists of 584 amino acids and predicts a molecular mass of 65.3 kDa. As a result of glycosylation, it migrates as an approximately 70-100 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameIL6R
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinterleukin 6 receptor
NCBI Gene AliasesCD126, HIES5, IL-1Ra, IL-6R, IL-6R-1, IL-6RA, IL6Q, IL6QTL, IL6RA, IL6RQ, gp80
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Developing drug-like single-domain antibodies (VHH) from in vitro librariesmAbsDecember 1, 2025Erasmus MF, Teixeira AAR, Molina E, Rodriguez Carnero LA, Li J, Knight D, Di Niro R, Leal-Lopes C, Fanni A, Troell H, et al.CT047-H08H), ADAMTS5 (R&D systems, # 2198-AD), IFN-α2 (Genscript, # Z03002), IL6R (Sino Biological, # 10398-H02H). Single-CDR library construction and heat shock filtering The libraries were built and filtered by

(2) Unveiling novel insights into human IL-6 - IL-6R interaction sites through 3D computer-guided docking and systematic site mutagenesisScientific reportsAugust 7, 2024Li K, Cai J, Jiang Z, Meng Q, Meng Z, Xiao H, Chen G, Qiao C, Luo L, Yu J, et al.h to prevent non-specific binding. hIL-6R with human Fc tag (Sino Biological, Beijing, China, Cat: 10398-H02H) was diluted to 0.075 − 7500 ng/mL. For the hIL-6R series dilution, 100 μL/well were added to the plate

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Human IL-6R / CD126 Protein (ECD, Fc Tag)

Human IL-6R / CD126 Protein (ECD, Fc Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IL-6R / CD126 Protein (ECD, Fc Tag) from Sino Biological, Inc.

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