Citrullinated Histone H3 (human, recombinant) 17926 from Cayman Chemical

Product Specs
ItemCitrullinated Histone H3 (human, recombinant)
CompanyCayman Chemical
Price $600.00Supplier Page View Company Product Page
Catalog Number17926
Size100 µg
ApplicationsImmunoreactive with anti-citrulline antibodies by Western blot and ELISA
Molecular Weight15.5 kDa
Specieshuman
Source/Expression SystemE. coli
NCBI Full Gene NameH3 clustered histone 1
NCBI Gene AliasesH3/A, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, HIST1H3A
Research AreaAutoimmunity, Cancer, Citrullinated, Citrullination, Epigenetics, Transcription, & Translation, Histones/Histone Peptides, Immunology & Inflammation, Innate Immunity, Multiple Sclerosis, NETosis, Neurodegenerative Disorders, Neuroscience, Rheumatoid Arthritis, Sepsis/Shock, Writers
FormatA solution in PBS, pH 7.4
Purity≥90% estimated by SDS-PAGE
Storage-80
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Extracellular histones: a unifying mechanism driving platelet-dependent extracellular vesicle release and thrombus formation in COVID-19Journal of Thrombosis and HaemostasisSeptember 1, 2024Alicia S. Eustes, Azaj Ahmed, Jagadish Swamy, Gokul Patil, Melissa Jensen, Katina M. Wilson, Shibani Kudchadkar, Abdul Wahab, Usha Perepu, Francis J. Miller, et al.ng/mL, designated as histone H3, New England Biolabs M2503S), H3Cit (500–25,000 ng/mL, Cayman Chemicals 17926), or nucleosomes (500–10,000 ng/mL, EMD Millipore 14–1057). Peak thrombin (nM), velocity index (nM/min),

(2) The Polyanionic Drug Suramin Neutralizes Histones and Prevents EndotheliopathyThe Journal of ImmunologyAugust 15, 2023Nuria Villalba, Adrian M. Sackheim, Michael A. Lawson, Laurel Haines, Yen-Lin Chen, Swapnil K. Sonkusare, Yong-Tao Ma, Jianing Li, Devdoot Majumdar, Beth A. Bouchard, et al.H1, H2a, H3, H4 histones (unfractionated histones) or citrullinated histone H3 (Cayman chemicals; #17926) were used for binding experiments. The changes in intrinsic suramin fluorescence emission were measured

(3) Cytotoxic CD8(+) T cells target citrullinated antigens in rheumatoid arthritisNature communicationsJanuary 19, 2023Moon JS, Younis S, Ramadoss NS, Iyer R, Sheth K, Sharpe O, Rao NL, Becart S, Carman JA, James EA, et al.cit-α-enolase, and histones cit-H2B, cit-H3 and cit-H4 (all from Cayman Chemical, 400076, 21585, 30133, 17926, and 17927); and the native forms of vimentin, fibrinogen, α-enolase, and histones H2B, H3.1 and H4

(4) Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarctionBasic Research in CardiologyDecember 1, 2021Thomas M. Hofbauer et al.plates for 2 h. Wells were incubated with 50 µl of undiluted plasma samples or citH3 standard (Cayman, 17926) for 1.5 h. Plates were then incubated with anti-citrullinated histone H3 (1:2000 in PBS + 1% bovine serum

(5) Citrullinated Histone H3 Mediates Sepsis-Induced Lung Injury Through Activating Caspase-1 Dependent Inflammasome PathwayFrontiers in immunologyJanuary 1, 2021Tian Y, Li P, Wu Z, Deng Q, Pan B, Stringer KA, Alam HB, Standiford TJ, Li Y.above-mentioned complete medium. The next day, cells were treated with 30 µg/ml CitH3 (Cayman chemical, #17926) or H3 (Cayman chemical, #10263) protein dissolved in opti-MEM medium for 5 h. Cell-free supernatant

(6) Citrullinated histone 3 causes endothelial barrier dysfunctionBiochemical and Biophysical Research CommunicationsSeptember 1, 2018Jamie E. Meegan, Xiaoyuan Yang, Richard S. Beard, Melanie Jannaway, Victor Chatterjee, Thomas E. Taylor-Clark, Sarah Y. Yuancell-cell adhesive barrier function [22]. Cells were stimulated with human recombinant H3Cit (Item No. 17926; Cayman Chemical, Ann Arbor, MI) or vehicle control (0.1% BSA in PBS) with or without inhibitors. Representative

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Citrullinated Histone H3 (human, recombinant) from Cayman Chemical

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Cayman Chemical

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Citrullinated Histone H3 (human, recombinant) from Cayman Chemical

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