Recombinant Human Alpha-synuclein protein monomer (Active) ab218818 from Abcam

Product Specs
ItemRecombinant Human Alpha-synuclein protein monomer (Active)
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab218818
Gene NameSNCA
Source/Expression SystemEscherichia coli
ActivityActive
SpeciesHuman
Molecule NameSNCA
TypeProteins
NCBI Full Gene Namesynuclein alpha
Research AreaNeuroscience
NCBI Gene AliasesNACP, PARK1, PARK4, PD1
ApplicationsFuncS, SDS-PAGE, WB
Size100 µg

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Fibrinogen exacerbates α-synuclein aggregation and mitochondrial dysfunction via alpha5beta3 integrin in Parkinson’s diseaseJournal of Advanced ResearchMarch 1, 2026Zifeng Huang, Jialing Zheng, Feilan Yuan, Hui Zhong, Ruoyang Yu, Yuqi Luo, Muwei Zhang, Shuhan Chen, Bibiao Shen, Zhenchao Xie, et al.preparation of α-Syn PFF and FG-α-syn PFF mixed fibrils, recombinant α-syn monomers (Abcam, Cat. No. ab218818) were constantly agitated in a thermomixer (at 1000 rpm and 37 °C) and dissolved in PBS to achieve a

(2) Novel Poly-Arginine Peptide R18D Reduces α-Synuclein Aggregation and Uptake of α-Synuclein Seeds in Cortical NeuronsBiomedicinesJanuary 7, 2025Emma C. Robinson, Anastazja M. Gorecki, Samuel R. Pesce, Vaishali Bagda, Ryan S. Anderton, Bruno P. Melonithe addition of 5 μL per well of (384-well plate) α-syn monomer (10 μM final concentration; Abcam, ab218818) and ThT (25 μM final concentration) in 5 µL PBS. To account for any background and non-specific fluorescence

(3) Nr1h4 and Thrb ameliorate ER stress and provide protection in the MPTP mouse model of Parkinson'sLife science allianceJuly 1, 2024Ahuja N, Gupta S, Arora R, Bhagyaraj E, Tiwari D, Kumar S, Gupta P.α-syn protein aggregates (active) (ab218819, 4 μg/ml; Abcam) and human α-syn protein monomer (active) (ab218818; Abcam). Immunostainings were performed as described previously. Differentiated SH-SY5Y cells were fixed

(4) Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effectsnpj Parkinson's DiseaseSeptember 10, 2022Philip Wing-Lok Ho et al.(MEFs; which does not express αSyn), and (2) a purified recombinant monomeric αSyn protein (Abcam™; #ab218818) (Supplementary Fig. 3). Two-way ANOVA analysis revealed significant effects of LRRK2 mutation (p <

(5) Spreading of Aggregated α-Synuclein in Sagittal Organotypic Mouse Brain SlicesBiomoleculesJanuary 19, 2022Uçar B, Stefanova N, Humpel C.human α-syn aggregate (control) (Abcam; ab218817), recombinant human α-syn monomer (active) (Abcam; ab218818), recombinant human α-syn aggregate (active) (Abcam; ab218819) and recombinant mouse α-syn aggregate

(6) α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor GlibenclamideeneuroJanuary 1, 2021E. Hill, R. Gowers, M. J. E. Richardson, M. J. Wallhuman α-syn aggregates were purchased from Abcam (ab218819) along with the corresponding monomers (ab218818). Dopamine (HB1835) and ZD 7288 (HB1152) were purchased from Hello Bio (HB1835). Glibenclamide (PHR1287)

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Recombinant Human Alpha-synuclein protein monomer (Active) from Abcam

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Recombinant Human Alpha-synuclein protein monomer (Active) from Abcam

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