Mouse TNFR1 / CD120a / TNFRSF1A Protein (Fc Tag) 50496-M02H from Sino Biological, Inc.

Product Specs
ItemMouse TNFR1 / CD120a / TNFRSF1A Protein (Fc Tag)
CompanySino Biological, Inc.
Price $1,938.00Supplier Page View Company Product Page
Catalog Number50496-M02H
Conjugate/TagC-human IgG1-Fc
Purity> 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe secreted recombinant mouse TNFRSF1A/Fc is a disulfide-linked homodimer. The reduced monomer consists of 424 amino acids and has a predicted molecular mass of 47.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm TNFRSF1A/Fc monomer is approximately 55 kDa due to glycosylation
SpeciesMouse
Molecule NameTNFRSF1A
Source/Expression SystemHEK293 Cells
Activity1. Measured by its binding ability in a functional ELISA. Immobilized Mouse TNF-alpha (Cat:50349-MNAE) at 2 µg/ml (100 µl/well) can bind Mouse TNFRSF1AhFc (Cat:50496-M02H), the EC50 of Mouse TNFRSF1AhFc is 1.5-9.0 ng/mL. 2. Measured by its ability to inhibit the TNFα-mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 15-65 ng/mL in the presence of 0.1 ng/mL of recombinant mouse TNFα
FormatLyophilized from sterile PBS, pH 7.4
Size1 mg

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(1) Identification of Anti-TNFα VNAR Single Domain Antibodies from Whitespotted Bambooshark (Chiloscyllium plagiosum)Marine drugsApril 29, 2022Zhao L, Chen M, Wang X, Kang S, Xue W, Li Z.onto a 96-well ELISA plate, then 50 µL TNFRSF1AhFc (20 ng/mL, Sino Biological, Beijing, China, Cat:50496-M02H) and 50 µL 3B11 (3 μM) was successively added to the wells. Control wells were added with 100 μL using

(2) Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cellsInternational immunopharmacologyFebruary 1, 2019Lu Y, Xu X, Jiang T, Jin L, Zhao XD, Cheng JH, Jin XJ, Ma J, Piao HN, Piao LX.

Mouse TNFR1 / CD120a / TNFRSF1A Protein (Fc Tag)