Human c-MET / HGFR Protein (His Tag) 10692-H08H from Sino Biological, Inc.

Product Specs
ItemHuman c-MET / HGFR Protein (His Tag)
CompanySino Biological, Inc.
Price $258.00Supplier Page View Company Product Page
Catalog Number10692-H08H
Size100 µg
FormatLyophilized from sterile 20mM Tris, 150mM NaCl, pH8.5
ActivityImmobilized Recombinant Human HGF / Hepatocyte Growth Factor Protein (Cat: 10463-HNAS) at 2µg/mL (100µL/well) can bind Recombinant Human c-MET / HGFR Protein (His Tag) (Cat: 10692-H08H), the EC50 is 16-48 ng/mL
NCBI Gene AliasesAUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met
NCBI Full Gene NameMET proto-oncogene, receptor tyrosine kinase
Source/Expression SystemHEK293 Cells
Molecule NameMET
SpeciesHuman
Molecular WeightThe mature form of recombinant human c-Met is a disulfide-linked heterodimer composed of proteolytically cleaved α and β subunits. Each α and β subunit together consists of 919 amino acids and has a predicted molecular mass of 103 (α=33 +β=70) kDa. As a result of glycosylation, rh c-MET heterodimer thus migrates with apparent molecular mass of approximately 45 kDa and 85 kDa respectively in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Conjugate/TagC-His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancerCell Reports MedicineApril 21, 2026Wenjing Ning, Han Liu, Hongye Zeng, Xiaojing Qin, Lin Xu, Shiting Yang, Yue Wang, Fentian Chen, Na Yuan, Xiaoqing Chen, et al.screening Recombinant hTROP2 (Sinobiological, 10428-H08H) and recombinant hc-Met (Sinobiological, 10692-H08H) were used for immunization, which was performed by Shenzhen Kangti Life Technology Co., Ltd. From isolated

(2) MET Enhances Amivantamab Binding to EGFR and Antibody‐Dependent Cellular ToxicityCancer ScienceJanuary 1, 2026Shigeki Sato, Neval Yilmaz, Sachiko Arai, Katsuya Sakai, Hiroki Sato, Yuya Murase, Tsukasa Ueda, Hayato Koba, Shigeki Nanjo, Yuichi Tambo, et al.recombinant human MET were purchased from Bio‐Techne R&D Systems (#11302‐ER) and Sino Biological (#10692‐H08H), respectively. For amivantamab observation, 5 μg/mL of amivantamab was incubated on a mica surface

(3) Solving the light chain mismatch of IgG-like bispecific antibody by utilizing 2A peptide based FaBody platformBiotechnology ReportsDecember 1, 2025Dong Li, Pengfan Zheng, Xuejing Yao, Baopeng Zhang, Jiekun Zhang, Yaocheng Qu, Shasha Yun, Yanzhen Li, Shanshan Chen, Jianmin FangBR100669). Human-HER2 (G&P Biosciences, Cat. No. FCL0220) and human-cMet (Sino Biological, Cat. No. 10692-H08H) antigens with His tags were diluted to 2.5 μ g/mL and 40 μ g/mL, respectively, and a two-fold dilution

(4) MYTX-011: a pH-dependent anti-cMET antibody-drug conjugate designed for enhanced payload delivery to cMET expressing tumor cellsMolecular cancer therapeuticsApril 30, 2024Gera N, Fitzgerald KM, Ramesh V, Patel P, Kanojia D, Colombo F, Kien L, Aoyama S, Xu L, Jean J, et al.antibody (Cat# 4722) was purchased from Sartorius. Recombinant c-MET antigens, i.e., human c-MET (Cat# 10692-H08H), cynomolgus c-MET (Cat# 90304-C08H), and mouse c-MET (Cat# 50622-M08H) were purchased from Sino Biological.

(5) Discovery of novel cMET-targeting antibody Fab drug conjugates as potential treatment for solid tumors with highly expressed cMETExpert opinion on biological therapyJuly 1, 2023Lim RK, Buschman M, Khasanov A, Ledesma A, Chen J, Nguyen T, Guo J, Li L, Huang J, Niu J, et al.

(6) Crizotinib-based proteolysis targeting chimera suppresses gastric cancer by promoting MET degradationCancer scienceMay 1, 2023Chen JJ, Jin JM, Gu WJ, Zhao Z, Yuan H, Zhou YD, Nagle DG, Xi QL, Zhang XM, Sun QY, et al.immunoprecipitating with CRBN and blotting with MET. 2.8 Microscale thermophoresis assay The labeled MET protein (#10692‐H08H; SinoBiological) was diluted with PBST (0.05% Tween‐20 in PBS), mixed with PRO‐6 E, CRO, or PRO‐6 E‐Me

(7) Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumorsInvestigational new drugsFebruary 1, 2021Yuan X, Sun Z, Yuan Q, Hou W, Liang Q, Wang Y, Mo W, Wang H, Yu M.

(8) Detection of colonic neoplasia in vivo using near-infrared-labeled peptide targeting cMetScientific reportsNovember 29, 2019Wu X, Zhou J, Wang F, Meng X, Chen J, Chang TS, Lee M, Li G, Li X, Appelman HD, et al.https://doi.org/10.1038/s41598-019-54385-7 8 www.nature.com/scientificreports www.nature.com/scientificreports/ (10692-H08H, Sino Biological Inc) for 4 rounds54. Candidate phages with the highest enrichment were selected for

(9) Anti-MET immunoPET for non-small cell lung cancer using novel fully human antibody fragmentsMolecular cancer therapeuticsNovember 1, 2014Li K, Tavaré R, Zettlitz KA, Mumenthaler SM, Mallick P, Zhou Y, Marks JD, Wu AM.used for the first round. Reduced amounts of MET protein from another supplier (Sino Biological Inc., 10692-H08H) were used for the following 2 rounds. ELISA Phage ELISA was performed as previously described (28)

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Human c-MET / HGFR Protein (His Tag)

Human c-MET / HGFR Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human c-MET / HGFR Protein (His Tag) from Sino Biological, Inc.

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