Cynomolgus / Rhesus IL23R / IL23 Receptor Protein (Fc Tag) 90123-C02H from Sino Biological, Inc.

Product Specs
ItemCynomolgus / Rhesus IL23R / IL23 Receptor Protein (Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number90123-C02H
Conjugate/TagC-human IgG1-Fc
Purity> 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant cynomolgus / rhesus IL23R comprises 571 amino acids and has a calculated molecular mass of 64.9 KDa
SpeciesCynomolgus, Rhesus
Molecule NameIL23R
Source/Expression SystemHEK293 Cells
ActivityMeasured by its binding ability in a functional ELISA. 1. Immobilized human IL23A-His+IL12B-His (Cat:CT012-H08H) at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc. The EC50 of Cynomolgus IL23R-Fc is 0.14-0.35 µg/ml. 2.Immobilized mouse mIL12Bh (m)+mIL23Ah (Cat:CT028-M08H) at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc (Cat:90123-C02H). The EC50 of Cynomolgus IL23R-Fc (Cat:90123-C02H) is 0.05-0.11 µg/ml
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg

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(1) Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel diseaseScientific reportsSeptember 30, 2021Roberts KJ, Cubitt MF, Carlton TM, Rodrigues-Duarte L, Maggiore L, Chai R, Clare S, Harcourt K, MacDonald TT, Ray KP, et al.from Sino Biologicals; Recombinant Human IL-23 (CT012-H08H), Recombinant cynomolgus monkey IL-23R-Fc (90123-C02H), Murine IL-23 (CT028-M08H), Recombinant marmoset IL-23 (CT037-C08H), from Sigma; Goat serum (G9023),

Cynomolgus / Rhesus IL23R / IL23 Receptor Protein (Fc Tag)