Human LIFR / CD118 Protein (His Tag) 10628-H08H from Sino Biological, Inc.

Product Specs
ItemHuman LIFR / CD118 Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10628-H08H
ActivityImmobilized LIF Protein, Human, Recombinant (hFc Tag)(Cat:14890-H02H) at 2 µg/mL (100 µL/well) can bind LIFR Protein, Human, Recombinant (His Tag)(Cat:10628-H08H), the EC50 is 60-360 ng/mL
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
NCBI Gene AliasesCD118, LIF-R, SJS2, STWS, SWS
NCBI Full Gene NameLIF receptor subunit alpha
Source/Expression SystemHEK293 Cells
Molecule NameLIFR
SpeciesHuman
Molecular WeightThe secreted recombinant human LIFR comprises 800 amino acids with a predicted molecular mass of 91 kDa. As a result of glycosylation, rhLIFR migrates as an approximately 125-135 kDa band in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Conjugate/TagC-His

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(1) Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in miceBMC immunologyAugust 22, 2024Zhao S, Deng H, Lu Y, Tao Y, Li D, Jiang X, Wei X, Chen X, Ma F, Wang Y, et al.

(2) Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesisBiochemical pharmacologyMay 1, 2024Di Giorgio C, Morretta E, Lupia A, Bellini R, Massa C, Urbani G, Bordoni M, Marchianò S, Lachi G, Rapacciuolo P, et al.

(3) Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinomaFrontiers in oncologyJanuary 1, 2023Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchianò S, Rosselli R, Sepe V, Rapacciuolo P, Moraca F, et al.

(5) A critical review of endogenous psychotoxins as a cause of schizophreniaCanadian Psychiatric Association journalApril 1, 1967Throme ML, Gowdey CW.

Human LIFR / CD118 Protein (His Tag)