Mouse CD64 / FCGR1 Protein (His Tag) 50086-M08H from Sino Biological, Inc.

Product Specs
ItemMouse CD64 / FCGR1 Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number50086-M08H
Activity1.Immobilized Anti-CD20 (Research Grade Rituximab Biosimilar)(IgG1) at 1 µg/mL can bind Mouse FcγRI / CD64 recombinant protein (Cat:50086-M08H), the EC50 is 16-35 ng/mL(Routinely tested). 2.Immobilized Anti-CD3 (Research Grade OKT3 Biosimilar)(mouse IgG2a) at 2 µg/mL (100 µL/well) can bind Recombinant Mouse CD64 / FCGR1 Protein (His Tag) (Cat: 50086-M08H), the EC50 is 0.8-2.4 ng/mL(QC tested). 3.Loaded Mouse FcγRI / CD64 recombinant protein(Cat:50086-M08H) on His1K Biosensor, can bind Anti-VEGF (Research Grade Bevacizumab Biosimilar)(IgG1) with an affinity constant of 0.12 µM as determined in a BLI assay (Sartorius Octet Red384) (Routinely tested). 4.Loaded Mouse FcγRI / CD64 recombinant protein(Cat:50086-M08H) on His1K Biosensor, can bind Anti-PD1(Research grade Nivolumab biosimilar) (IgG4) with an affinity constant of 0.28 µM as determined in a BLI assay (Sartorius Octet Red384) (Routinely tested). 5.Captured Mouse FcγRI / CD64 recombinant protein(Cat:50086-M08H) on Anti-His Chip can bind Anti-VEGF (Research Grade Bevacizumab Biosimilar)(IgG1) with an affinity constant of 0.12 µM as determined in an SPR assay (Biacore T200) (Routinely tested). 6.Captured Mouse FcγRI / CD64 recombinant protein (Cat:50086-M08H) on Anti-His Chip can bind Anti-PD1(Research grade Nivolumab biosimilar) (IgG4) with an affinity constant of 0.69 µM as determined in an SPR assay (Biacore T200) (Routinely tested). 7.Loaded Anti-CD3 (Research Grade OKT3 Biosimilar)(mouse IgG2a) on ProA Biosensor, can bind Recombinant Mouse CD64 Protein, His Tag (Cat. No. 50086-M08H) with an affinity constant of 3.46nM as determined in BLI assay (Sartorius Octet RED384)(QC tested). 8.Loaded Recombinant Mouse CD64 Protein, His Tag (Cat. No. 50086-M08H) on His1K Biosensor, can bind Anti-CD3 (Research Grade OKT3 Biosimilar)(mouse IgG2a) with an affinity constant of 26.7nM as determined in BLI assay (Sartorius Octet RED384)(Routinely tested). 9.Immobilized Recombinant Mouse CD64 / FCGR1 Protein (His Tag) (Cat: 50086-M08H) at 5 µg/mL (100 µL/well) can bind Anti-CD3 (OKT3) (Research Grade Muromonab Biosimilar), Biotinylated, the EC50 is 113.4 ng/mL (Routinely tested). 10.Loaded Anti-HER2 (Research Grade Trastuzumab Biosimilar) (Cat. No. 68046-H002) on ProA Biosensor, can bind Recombinant Mouse CD64 / FCGR1 Protein (His Tag) (Cat. No. 50086-M08H) with an affinity constant of 47.8 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
NCBI Gene AliasesCD64, FcgammaRI, IGGHAFC
NCBI Full Gene NameFc receptor, IgG, high affinity I
Source/Expression SystemHEK293 Cells
Molecule NameFCGR1
SpeciesMouse
Molecular WeightThe recombinant mouse FCGR1 consists of 284 amino acids after removal of the signal peptide and has a predicted molecular mass of 32 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FCGR1 is approximately 45-50 kDa due to glycosylation. The molecular weight of this protein is around 40-50 kDa verified by SEC-MALS (Routinely tested)
TypeRecombinant protein
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. ≥ 90 % as determined by SEC-MALS(Routinely tested)
Conjugate/TagC-His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptorsmAbsDecember 31, 2024Geoff Hale, Jelle De Vos, Alastair Douglas Davy, Koen Sandra, Ian Wilkinson,Sino Biological,90014-C08H FcγRIIIa (CD16a),cynomolgus,Sino Biological,90013-C08H FcγRI (CD64),mouse,Sino Biological,50086-M08H FcγRIV (CD16-2),mouse,Sino Biological,50036-M08H

(2) An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine ImmunogenicityInternational journal of nanomedicineJanuary 1, 2024Chiu CT, Tsai HH, Chen JY, Hu CJ, Chen HW.(CR1) (R&D Systems #5748-CD-050, NE Minneapolis, MN) and mouse CD64/FCGR1 protein (Sino Biological #50086-M08H). Afterward, the primary antibodies, including rabbit CD35 polyclonal antibody (Invitrogen #PA5-114324)

(3) Microglia actively remove NR1 autoantibody-bound NMDA receptors and associated post-synaptic proteins in neuron microglia co-culturesGliaAugust 1, 2023Rahman KA, Orlando M, Boulos A, Andrzejak E, Schmitz D, Ziv NE, Prüss H, Garner CC, Ichkova A.

(4) Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse ModelNeuronFebruary 19, 2020Nguyen L, Montrasio F, Pattamatta A, Tusi SK, Bardhi O, Meyer KD, Hayes L, Nakamura K, Banez-Coronel M, Coyne A, et al.Antibody affinity for murine Fc receptor subtypes was determined using His-tagged mouse CD64/FCΓR1 (#50086-M08H, Sino Biological), CD32/FCΓR2 (#50030-M08H, Sino Biological), CD16/FCΓR3 (#50326-M08H, Sino Biological)

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Mouse CD64 / FCGR1 Protein (His Tag)

Mouse CD64 / FCGR1 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse CD64 / FCGR1 Protein (His Tag) from Sino Biological, Inc.

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