Human IL18RAP / IL1R7 Protein (Fc Tag) 10176-H02H from Sino Biological, Inc.

Product Specs
ItemHuman IL18RAP / IL1R7 Protein (Fc Tag)
CompanySino Biological, Inc.
Price $198.00Supplier Page View Company Product Page
Catalog Number10176-H02H
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
ActivityRecombinant Human IL-18R beta / IL-18RAP Protein, hFc Tag (Cat. No. 10176-H02H) captured on Protein A chip can bind Recombinant Human IL-18 Protein (Cat. No. 10119-HNCE) (Premixed with Recombinant Human IL-18Rα Protein, His Tag, Cat. No. 11102-H08H) with an affinity constant of 12.85 nM as determined in an SPR assay (Biacore T200) (Routinely tested)
NCBI Gene AliasesACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB
NCBI Full Gene Nameinterleukin 18 receptor accessory protein
Source/Expression SystemHEK293 Cells
Molecule NameIL18RAP
SpeciesHuman
Molecular WeightThe recombinant human IL18RAP/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 575 amino acids and has a calculated molecular mass of 65.2 kDa. As a result of glycosylation, the apparent molecular mass of rhIL18RAP/Fc monomer is approximately 80-90 kDa in reduced SDS-PAGE
TypeRecombinant protein
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Conjugate/TagC-human IgG1-Fc

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(1) Structure-Guided Stapling of Dimeric Conformations and Linker Engineering Enhance Thermostability and Fine-Tune Activity of Bispecific VHH Cytokine AgonistsAntibodies (Basel)September 1, 2025Raphael Trenker, Deepti Rokkam, Andrew Morin, Priyanka Balasubrahmanyam, Verenice Paredes, Ivan Cheng, Rene de Waal Malefyt, Martin Oft, Patrick Lupardus, Sandro VivonaIL-18Rβ ECDs fused to human Fc for SPR experiments were purchased from Sino Biological (11102-H02H, 10176-H02H). Other proteins were expressed via transfection of CMV promoter vectors into Expi293 cells treated

Human IL18RAP / IL1R7 Protein (Fc Tag)