Human IL1R2 / IL1RB / CD121b Protein (ECD, His Tag) 10111-H08H from Sino Biological, Inc. | Biocompare.com

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Human IL1R2 / IL1RB / CD121b Protein (ECD, His Tag)

Human IL1R2 / IL1RB / CD121b Protein (ECD, His Tag)

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Sino Biological, Inc. for
Human IL1R2 / IL1RB / CD121b Protein (ECD, His Tag)

Description

A DNA sequence encoding the extracellular domain (Met 1-Glu 343) of human IL1R2 (NP_004624.1) was expressed, with a fused C-terminal polyhistidine tag

Product Specs
ItemHuman IL1R2 / IL1RB / CD121b Protein (ECD, His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10111-H08H
Size100 µg
Conjugate/TagC-His
Purity> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human IL1R2 consists of 341 amino acids and has a predicted molecular mass of 39.2 kDa. As a result of glycosylation, the rh IL1R2 migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameIL1R2
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinterleukin 1 receptor type 2
NCBI Gene AliasesCD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
ActivityMeasured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500pg/mL IL1b. The EC50 for this effect is typically 20-80ng/mL
FormatLyophilized from sterile PBS, pH 7.4

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Sino Biological, Inc.

Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 ImmunotherapyCancer researchDecember 1, 2025Arnouk SM, Kancheva D, Van Damme H, Courtoy GE, Mora Barthelmess R, Van Craenenbroeck J, Lebegge E, Elkrim Y, Assaf N, Heremans Y, et al.

(2) Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological systemCommunications biologyJuly 18, 2024Rigal S, Casas B, Kanebratt KP, Wennberg Huldt C, Magnusson LU, Müllers E, Karlsson F, Clausen M, Hansson SF, Leonard L, et al.

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