Mouse CD16 / FCGR3 Protein (ECD,His Tag) 50326-M08H from Sino Biological, Inc.

Product Specs
ItemMouse CD16 / FCGR3 Protein (ECD,His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number50326-M08H
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe secreted recombinant mouse FCGR3 consists of 196 amino acids and has a predicted molecular mass of 22.6 kDa. As a result of glycosylation, the apparent molecular mass of mouse FCGR3 is approximately 35-44 kDa in SDS-PAGE under reducing conditions
SpeciesMouse
Molecule NameFCGR3
Source/Expression SystemHEK293 Cells
Activity1.Loaded Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) on ProA Biosensor, can bind Recombinant Mouse CD16/FCGR3 Protein, His Tag (Cat. No. 50326-M08H) with an affinity constant of 322nM as determined in BLI assay (Sartorius Octet RED384)(Routinely tested). 2.Loaded Recombinant Mouse CD16/FCGR3 Protein, His Tag (Cat. No. 50326-M08H) on His1K Biosensor, can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) with an affinity constant of 18.5nM as determined in BLI assay (Sartorius Octet RED384)(Routinely tested). 3.Loaded Recombinant Mouse CD16/FCGR3/Fc gamma RIII Protein, His Tag (Cat. No. 50326-M08H) on NTA Biosensor, can bind Herceptin derived Anti-Erbb2 Antibody, Human IgG1 with an affinity constant of 2.790 µM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 4.OKT3 derived Anti-CD3 antibody, mouse IgG2a immobilized on CM5 chip, can bind Recombinant Mouse CD16/FCGR3/Fc gamma RIII Protein, His Tag (Cat. No. 50326-M08H) with an affinity constant of 0.953 µM as determined in an SPR assay (Biacore 8K) (QC tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Antibody therapeutics with high affinity for FcγRs exacerbate anaphylaxis via FcγR-mediated capture by tumor-associated myeloid cellsJ Immunother CancerMarch 4, 2026Ruiheng Tang, Aizemaiti Aizemaiti, Yuta Tamemoto, Riho Kume, Kazuto Yasuda, Kenta Sato, Hirohito Abo, Kazuto Tsuji, Kyohei Higashi, Masato Kiyoshi, et al.8K instrument (Cytiva). His-tagged recombinant mouse FcγRIIIa (mouse CD16) (Sino Biologicals, Cat# 50326-M08H), and mouse FcγRIV (mouse CD16-2) (Sino Biologicals, Cat# 50036-M08H) were used as immobilized ligands.

(2) Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse ModelNeuronFebruary 19, 2020Nguyen L, Montrasio F, Pattamatta A, Tusi SK, Bardhi O, Meyer KD, Hayes L, Nakamura K, Banez-Coronel M, Coyne A, et al.CD64/FCΓR1 (#50086-M08H, Sino Biological), CD32/FCΓR2 (#50030-M08H, Sino Biological), CD16/FCΓR3 (#50326-M08H, Sino Biological) and FCΓRT & B2M heterodimer proteins (#CT029-M08H, Sino Biological) from solubilized

(3) Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and miceMolecular immunologyFebruary 1, 2018Dekkers G, Bentlage AEH, Plomp R, Visser R, Koeleman CAM, Beentjes A, Mok JY, van Esch WJE, Wuhrer M, Rispens T, et al.

(4) Affinity of human IgG subclasses to mouse Fc gamma receptorsmAbsJuly 1, 2017Dekkers G, Bentlage AEH, Stegmann TC, Howie HL, Lissenberg-Thunnissen S, Zimring J, Rispens T, Vidarsson G.

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Mouse CD16 / FCGR3 Protein (ECD,His Tag)

Mouse CD16 / FCGR3 Protein (ECD,His Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (4)

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Mouse CD16 / FCGR3 Protein (ECD,His Tag) from Sino Biological, Inc.

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