Human DCR3 / TNFRSF6B Protein (Fc Tag) 10224-H02B from Sino Biological, Inc.

Product Specs
ItemHuman DCR3 / TNFRSF6B Protein (Fc Tag)
CompanySino Biological, Inc.
Price $398.00Supplier Page View Company Product Page
Catalog Number10224-H02B
Conjugate/TagC-human IgG1-Fc
Purity> 85 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human DCR3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 508 amino acids and has a predicted molecular mass of 56.4 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameTNFRSF6B
Source/Expression SystemBaculovirus-Insect Cells
NCBI Full Gene NameTNF receptor superfamily member 6b
NCBI Gene AliasesDCR3, DJ583P15.1.1, M68, M68E, TR6
Activity1.Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 3-25 µg/mL in the presence of 200 ng/mL recombinant human Fas ligand. 2.Immobilized Recombinant Human DCR3 / TNFRSF6B Protein (Fc Tag) (Cat: 10224-H02B) at 2 µg/mL (100 µl/well) can bind Recombinant Human TL1A / TNFSF15 Protein (His Tag) (Cat: 17049-H07H), the EC50 is 60-180 ng/mL. 3.Loaded Recombinant Human DcR3/TNFRSF6B Protein, hFc Tag (Cat. No. 10224-H02B ) on ProA Biosensor, can bind Recombinant Cynomolgus, Rhesus TL1A/TNFSF15 Protein, His Tag (Cat. No. 91015-C07H1) with an affinity constant of 4.02 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 4.Recombinant Human DcR3/TNFRSF6B Protein, hFc Tag (Cat. No. 10224-H02B) captured on Protein A chip can bind Recombinant Human TL1A/TNFSF15 Protein (Trimer), His Tag (Cat. No. 17049-H07H2) with an affinity constant of 27.64 pM as determined in an SPR assay (Biacore T200) (Routinely tested)
FormatLyophilized from sterile 100mM Glycine, 10mM NaCl, pH 7.0
Size100 µg