Human CD33 / Siglec-3 Protein (ECD,His Tag) 12238-H08H from Sino Biological, Inc.

Product Specs
ItemHuman CD33 / Siglec-3 Protein (ECD,His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number12238-H08H
Conjugate/TagC-His
Purity≥ 90 % as determined by SDS-PAGE ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human CD33 comprises 253 amino acids and has a predicted molecular mass of 28.2 kDa. The apparent molecular mass of the protein is approximately 40-46 kDa in SDS-PAGE under reducing conditions due to glycosylation
SpeciesHuman
Molecule NameCD33
Source/Expression SystemHEK293 Cells
FormatLyophilized from sterile 10mM NaH₂PO₄,2mM EDTA, 150mM NaCl, pH 7.2
Size100 µg
Activity1.Immobilized Anti-CD33 Antibody (Lintuzumab), Human IgG1 at 2 µg/ml (100 µl/well) can bind Recombinant Human CD33 / Siglec-3 Protein (ECD,His Tag) (Cat: 12238-H08H), the EC50 is 1.5-6 ng/mL. 2.Loaded anti-CD33 antibody on ProA Biosensor, can bind Recombinant Human Siglec-3/CD33 Protein, His Tag (Cat. No. 12238-H08H) with an affinity constant of 0.379 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Discovery and preclinical development of a SdAb-based CAR-T technology for targeting CD33 in AMLMolecular Therapy OncologyMarch 20, 2025Franco Bernasconi-Bisio, Eva Molina, Vianca Ibarra, Inés Ibáñez-Sala, Federica Rochira, Patricia Jauregui, Saray Rodríguez-Diaz, Rebeca Martínez-Turrillas, Iñigo Azagra-Barber, Nuria Gómez-Cebrián, et al.immune SdAb library A male llama was immunized with the CD33 recombinant ectodomain (SinoBiological #12238-H08H) four times in-between 20 and 30 days at doses of 150 and 200 μg, alongside other antigens (SLAMF7,

(2) T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemiaJournal for immunotherapy of cancerMay 1, 2021Hoseini SS, Vadlamudi M, Espinosa-Cotton M, Tran H, Feng Y, Guo HF, Xu H, Cheung I, Cheung NV.and complement binding, respectively.6 Surface plasmon resonance Human CD33 (Sino Biological, Cat # 12238-H08H) was immobilized on a CM5 chip. Serial twofold dilutions of the BsAbs (starting at 100 nM) were flowed

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Human CD33 / Siglec-3 Protein (ECD,His Tag)

Human CD33 / Siglec-3 Protein (ECD,His Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (2)

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Human CD33 / Siglec-3 Protein (ECD,His Tag) from Sino Biological, Inc.

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