Human ACVR2B / ActivinR-IIB Protein (His Tag) 10229-H08H from Sino Biological, Inc.

Product Specs
ItemHuman ACVR2B / ActivinR-IIB Protein (His Tag)
CompanySino Biological, Inc.
Price $858.00Supplier Page View Company Product Page
Catalog Number10229-H08H
Size500 µg
Conjugate/TagC-His
Purity≥ 97 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human ACVR2B comprises 127 amino acids and predicts a molecular mass of 15 kDa. As a result of glycosylation, rh ACVR2B migrates as an approximately 33-38 kDa protein in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameACVR2B
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameactivin A receptor type 2B
NCBI Gene AliasesACTRIIB, ActR-IIB, HTX4
Activity1.Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.3-2 µg/mL in the presence of 10 ng/mL recombinant Activin A(Routinely tested). 2.Recombinant Human ACVR2B Protein, His Tag (Cat. No. 10229-H08H) immobilized on CM5 chip can bind Recombinant Mouse Activin A Protein, His Tag (Cat. No. 50659-M08H) with an affinity constant of 2.420 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 3.Recombinant Human ACVR2B / ActivinR-IIB Protein (His Tag) (Cat: 10229-H08H) immobilized on CM5 chip, can bind Recombinant Human/Mouse/Rat/Cynomolgus/Rhesus Activin A/INHBA Protein (Cat: 10429-HNAH) with an affinity constant of 0.239 nM as determined in an SPR assay (Biacore 8K) (QC tested)
FormatLyophilized from sterile PBS, pH 7.4