Mouse IL2RA / CD25 Protein (ECD, His Tag) 50292-M08H from Sino Biological, Inc.

Product Specs
ItemMouse IL2RA / CD25 Protein (ECD, His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number50292-M08H
Conjugate/TagC-His
Purity≥ 98 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe secreted recombinant mouse IL2RA cmprises 226 amino acids with a predicted molecular mass of 26 kDa. As a result of glycosylation, the apparent molecular mass of the rm IL2RA is approximately 50-55 kDa in SDS-PAGE under reducing conditions
SpeciesMouse
Molecule NameIL2RA
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinterleukin 2 receptor, alpha chain
NCBI Gene AliasesCD25, Il2r, Ly-43
FormatLyophilized from sterile PBS, pH 7.4
ActivityImmobilized Recombinant Human IL2 Protein,Low Endotoxin(Cat:11848-HNAH1-E) at 2 µg/ml (100 µl/well) can bind Recombinant Mouse IL2RA / CD25 Protein (ECD,His Tag)(Cat:50292-M08H),The EC50 is 410-900 ng/mL
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Targeting of specific neuronal types in the non-human primate brain by using a murine CD25-specific recombinant immunotoxinScientific ReportsFebruary 11, 2026Tomoko Kobayashi, Shigeki Kato, Shingo Kimura, Masateru Sugawara, Kanichiro Ihara, Tatsuhiko Ozawa, Ken-ichi Inoue, Masahiko Takada, Masanori Onda, Kazuto Kobayashirabbit was immunized subcutaneously with 500 µg of purified mCD25/His-tag (Sino Biological Inc., Cat#50292-M08H) in Freund’s complete adjuvant (Sigma-Aldrich, Cat#AR001). Two, 4, and 6 weeks after the primary immunization,

(2) Adiponectin-expressing Treg-containing T cell fraction inhibits tumor growth in orthotopically implanted triple-negative breast cancerThoracic cancerOctober 1, 2023Chikaishi W, Higashi T, Hayashi H, Hanamatsu Y, Futamura M, Matsuhashi N, Saigo C, Takeuchi T.and monoclonal rabbit anti‐mouse CD25 conjugated with fluorescein isothiocyanate (FITC) (catalog no. 50292‐M08H, Sino Biological, Inc.). The following antibodies were used for fluorescent immunohistochemistry: rabbit

(3) Potential activity of adiponectin-expressing regulatory T cells against triple-negative breast cancer cells through the cell-in-cell phenomenonThoracic cancerJuly 1, 2023Chikaishi W, Higashi T, Hayashi H, Hanamatsu Y, Kito Y, Futamura M, Matsuhashi N, Saigo C, Takeuchi T.monoclonal antibody against mouse CD25 conjugated with fluorescein isothiocyanate (FITC) (catalog no. 50292‐M08H) was obtained from Sino Biological Inc. Rabbit anti‐adiponectin antibody (cat. no. GTX107737, GeneTex

(4) Adiponectin-expressing Treg cells in experimental thymic tumor modelThoracic cancerFebruary 1, 2023Hanamatsu Y, Saigo C, Takeuchi T.no. 1102040: Sony), while rabbit monoclonal antibody to mouse CD25 conjugated with FITC (catalog no. 50292‐M08H: Sino Biological Inc). In brief, cells were incubated with or without 1:100 diluted antibodies at 4°C

(5) CD25-T(reg)-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunityNature cancerDecember 1, 2020Solomon I, Amann M, Goubier A, Arce Vargas F, Zervas D, Qing C, Henry JY, Ghorani E, Akarca AU, Marafioti T, et al.properties of surrogate murine αCD25-antibodies by SPR-experiments His-tagged murine CD25 antigen 50292-M08H was purchased from Sino Biological. All SPR experiments were performed on a BIAcore© B2000 instrument

(6) Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunityProceedings of the National Academy of Sciences of the United States of AmericaMarch 5, 2019Onda M, Kobayashi K, Pastan I.2E4-PE38 as described previously (33). Briefly, ELISA plates were coated with 1 μg/mL of mouse CD25 protein (#50292-M08H; Sino Biological) in PBS at 4 °C overnight. Diluted standards or serum samples were applied, followed

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Mouse IL2RA / CD25 Protein (ECD, His Tag)

Mouse IL2RA / CD25 Protein (ECD, His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse IL2RA / CD25 Protein (ECD, His Tag) from Sino Biological, Inc.

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