Human CD46 Protein (His Tag) 12239-H08H from Sino Biological, Inc.

Product Specs
ItemHuman CD46 Protein (His Tag)
CompanySino Biological, Inc.
Price $1,688.00Supplier Page View Company Product Page
Catalog Number12239-H08H
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human CD46 consists of 305 amino acids and has a predicted molecular mass of 34 kDa. As a result of glycosylation, the apparent molecular mass of rh CD46 is approximately 55-60 kDa in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameCD46
Source/Expression SystemHEK293 Cells
FormatLyophilized from sterile PBS, pH 7.4
Size500 µg
Activity1.Loaded YS5FL derived anti-CD46 antibody, human IgG1 on proA Biosensor, can bind Recombinant Human CD46 Protein, His Tag (Cat. No. 12239-H08H) with an affinity constant of 0.737 µM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Immobilized Recombinant Human CD46 Protein (His Tag) (Cat: 12239-H08H) at 1 µg/mL (100 µL/well) can bind YS5FL derived Anti-CD46 antibody, the EC50 is 3.5-11.0 ng/mL (QC tested)

Add to Compare List

Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) In vivo HSC transduction in rhesus macaques with an HDAd5/3+ vector targeting desmoglein 2 and transiently overexpressing cxcr4Blood advancesAugust 9, 2022Wang H, Germond A, Li C, Gil S, Kim J, Kiem HP, Lieber A.(Fenton, MO; catalog no. D340) and recombinant CD46 from Sino Biological (Beijing, China; catalog no. 12239-H08H). Both recombinant proteins were produced in mammalian cells as Fc fusion protein (DSG2) or with His

(2) Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46Proceedings of the National Academy of Sciences of the United States of AmericaJanuary 19, 2021Persson BD, John L, Rafie K, Strebl M, Frängsmyr L, Ballmann MZ, Mindler K, Havenga M, Lemckert A, Stehle T, et al.the HAdV-D56–CD46 Complex. Purified HAdV-D56 virions and purified recombinant CD46 (Sino Biological; 12239-H08H) were used at 1.2 and 0.5 mg/mL in PBS (pH 7.4), respectively. Samples were vitrified on Quantifoil

(3) CD46 facilitates entry and dissemination of human cytomegalovirusNature communicationsJune 20, 2019Stein KR, Gardner TJ, Hernandez RE, Kraus TA, Duty JA, Ubarretxena-Belandia I, Moran TM, Tortorella D.or otherwise noted) or soluble proteins Nrp2 (P) and CD46 (P) (Sino Biological (cat#: 10695-H08H and 12239-H08H) for 1 h 4 °C was used to infect ARPE-19, HTR-8/SVneo, or MRC5 cells (1 × 104 cell/well in a 96-well

(4) Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactionsNature communicationsFebruary 14, 2019Baker AT, Greenshields-Watson A, Coughlan L, Davies JA, Uusi-Kerttula H, Cole DK, Rizkallah PJ, Parker AL.Catalogue number 3336-CX-050. Recombinant Human CD46 Protein (His Tag), Sino Biological, Catalogue number 12239-H08H. Reporting summary Further information on experimental design is available in the Nature Research

(5) Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeuticMolecular therapy. Methods & clinical developmentJanuary 1, 2016Richter M, Yumul R, Saydaminova K, Wang H, Gough M, Baldessari A, Cattaneo R, Lee F, Wang CH, Jang H, et al.

(6) Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies?Journal of neuroimmunologyNovember 15, 2014Miyaji K, Paul F, Shahrizaila N, Umapathi T, Yuki N.

(7) C1q binding to dengue virus decreases levels of infection and inflammatory molecules transcription in THP-1 cellsVirus researchJanuary 22, 2014Douradinha B, McBurney SP, Soares de Melo KM, Smith AP, Krishna NK, Barratt-Boyes SM, Evans JD, Nascimento EJ, Marques ET Jr.

Be the First to Write a Review!

Human CD46 Protein (His Tag)

Human CD46 Protein (His Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (7)

Reviews

Human CD46 Protein (His Tag) from Sino Biological, Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map