Mouse CD16-2 / FCGR4 Protein (His Tag) 50036-M08H from Sino Biological, Inc.

Product Specs
ItemMouse CD16-2 / FCGR4 Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number50036-M08H
Activity1.Loaded Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) on ProA Biosensor, can bind Recombinant Mouse FCGR4 Protein, His Tag (Cat. No. 50036-M08H) with an affinity constant of 3.43nM as determined in BLI assay (Sartorius Octet RED384)(QC tested). 2.Loaded Recombinant Mouse FCGR4 Protein, His Tag (Cat. No. 50036-M08H) on His1K Biosensor, can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) with an affinity constant of 17.7nM as determined in BLI assay (Sartorius Octet RED384)(Routinely tested). 3.Loaded Recombinant Mouse CD16-2/FCGR4/Fc gamma RIV Protein, His Tag (Cat. No. 50036-M08H) on NTA Biosensor, can bind Herceptin derived Anti-Erbb2 Antibody, Human IgG1 with an affinity constant of 69.300 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 4.Recombinant Mouse CD16-2/FCGR4/Fc gamma RIV Protein, His Tag (Cat. No. 50036-M08H) captured on CM5 chip via Anti-his antibody, can bind OKT3 derived Anti-CD3 antibody, mouse IgG2a with an affinity constant of 0.228 µM as determined in an SPR assay (Biacore T200) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
NCBI Gene Aliases4833442P21Rik, CD16-2, FcgRIV, FcgammaRIV, Fcgr3a, Fcrl3
NCBI Full Gene NameFc receptor, IgG, low affinity IV
Source/Expression SystemHEK293 Cells
Molecule NameFCGR4
SpeciesMouse
Molecular WeightThe recombinant mouse FCGR4 consists of 194 amino acids and has a predicted molecular mass of 22.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmFCGR4 is approximately 25-35 kDa due to glycosylation
TypeRecombinant protein
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Conjugate/TagC-His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Antibody therapeutics with high affinity for FcγRs exacerbate anaphylaxis via FcγR-mediated capture by tumor-associated myeloid cellsJ Immunother CancerMarch 4, 2026Ruiheng Tang, Aizemaiti Aizemaiti, Yuta Tamemoto, Riho Kume, Kazuto Yasuda, Kenta Sato, Hirohito Abo, Kazuto Tsuji, Kyohei Higashi, Masato Kiyoshi, et al.CD16) (Sino Biologicals, Cat# 50326-M08H), and mouse FcγRIV (mouse CD16-2) (Sino Biologicals, Cat# 50036-M08H) were used as immobilized ligands. The FcγRs were immobilized on a CM5 chip using a His Capture Kit

(2) Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptorsmAbsDecember 31, 2024Geoff Hale, Jelle De Vos, Alastair Douglas Davy, Koen Sandra, Ian Wilkinson,Sino Biological,90013-C08H FcγRI (CD64),mouse,Sino Biological,50086-M08H FcγRIV (CD16-2),mouse,Sino Biological,50036-M08H

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Mouse CD16-2 / FCGR4 Protein (His Tag)

Mouse CD16-2 / FCGR4 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse CD16-2 / FCGR4 Protein (His Tag) from Sino Biological, Inc.

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