Human CD112 / Nectin-2 / PVRL2 Protein (Fc Tag) 10005-H02H from Sino Biological, Inc.

Product Specs
ItemHuman CD112 / Nectin-2 / PVRL2 Protein (Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10005-H02H
Size100 µg
Conjugate/TagC-human IgG1-Fc
Purity> 95 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant mature human CD112/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 567 amino acids and has a calculated molecular mass of 62.3 kDa. As a result of glycosylation, the rh CD112/Fc monomer migrates as an approximately 70-80 kDa protein in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameNECTIN2
Source/Expression SystemHEK293 Cells
NCBI Full Gene Namenectin cell adhesion molecule 2
NCBI Gene AliasesCD112, HVEB, PRR2, PVRL2, PVRR2
Activity1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 µg/ml (100 µl/well) can bind human CD112 with a linear range of 6.4-800 ng/ml. 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag)(Cat:90971-C08H) at 2 µg/ml (100 µl/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag)(Cat:10005-H02H), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL. 3.Loaded Human PVRIG Protein, mFc Tag(Cat.No.28312-H38H2) on AMC Biosensor, can bind Human Nectin-2 protein, hFc Tag (Cat.No.10005-H02H) with an affinity constant of 8.784nM as determined in BLI assay (Sartorius Octet Red384) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4