Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag) 10594-H08H1 from Sino Biological, Inc.

Product Specs
ItemHuman PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag)
CompanySino Biological, Inc.
Price $1,288.00Supplier Page View Company Product Page
Catalog Number10594-H08H1
Activity1.Immobilized Recombinant Human LDL Receptor Protein (Fc Tag) (Cat: 10231-H05H) at 2 µg/ml (100 µl/well) can bind Recombinant Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag) (Cat: 10594-H08H1), the EC50 of Recombinant Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein (His Tag) is 8-26 ng/mL. 2.Loaded Recombinant Human LDLR/LDL Receptor Protein, mFc Tag (Cat. No. 10231-H05H) on ProA Biosensor, can bind Human PCSK9 / NARC1 (D374Y, V474I, G670E) Protein, His Tag (Cat. No. 10594-H08H1) with an affinity constant of 3.08nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
FormatLyophilized from sterile 20mM Tris, 100mM NaCl, 10% Glycerol, 0.01% Tween20, pH 8.5
Size500 µg
Source/Expression SystemHEK293 Cells
Molecule NamePCSK9
SpeciesHuman
Molecular WeightThe recombinant human PCSK9 consists 673 amino acids and predicts a molecular mass of 72.6 kDa. As a result of glycosylation and proteolytic digestion, it migrates as doublet with apparent molecular mass of 19 kDa and 60 kDa corresponding to the pro domain and mature form respectively in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Conjugate/TagC-His