Human LDLR / LDL Receptor Protein (His Tag) 10231-H08H from Sino Biological, Inc.

Product Specs
ItemHuman LDLR / LDL Receptor Protein (His Tag)
CompanySino Biological, Inc.
Price $198.00Supplier Page View Company Product Page
Catalog Number10231-H08H
Size50 µg
Conjugate/TagC-His
Purity≥ 85 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe secreted recombinant human LDLR comprises 777 amino acids with a predicted molecular mass of 86 kDa. As a result of different glycosylation, it migarates with the apparent molecular mass of 110-140 kDa in SDS-PAGE under reducing conditions corresponding to the mature and immature form
SpeciesHuman
Molecule NameLDLR
Source/Expression SystemHEK293 Cells
NCBI Full Gene Namelow density lipoprotein receptor
NCBI Gene AliasesFH, FHC, FHCL1, LDLCQ2
ActivityImmobilized Human LDLR/LDL Receptor His (Cat:10231-H08H) at 2 µg/mL (100 µL/well) can bind Mouse PCSK9 mFc (Cat:50251-M05H), the EC50 of Mouse PCSK9 mFc (Cat:50251-M05H) is 100-800 ng/mL
FormatLyophilized from sterile PBS, pH 7.4

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Biparatopic anti-PCSK9 antibody enhances the LDL-uptake in HepG2 cellsScientific ReportsJuly 3, 2024Xinyang Li, Wei Zhang, Yu Shu, Rui Huo, Chengyang Zheng, Qi Qi, Pengfei Fu, Jie Sun, Yuhuan Wang, Yan Wang, et al.the efficiency of the novel Ab in inhibiting PCSK9’s binding to LDLR. Briefly, LDLR-his protein (Cat# 10231-H08H, Sinobiological, China) was first diluted to a concentration of 1 μg/mL. Subsequently, 100 ng (100 μL)

(2) The Immunoglobulin Superfamily Receptome Defines Cancer-Relevant Networks Associated with Clinical OutcomeCellJuly 23, 2020Verschueren E, Husain B, Yuen K, Sun Y, Paduchuri S, Senbabaoglu Y, Lehoux I, Arena TA, Wilson B, Lianoglou S, et al.

(3) Binding of Macrophage Receptor MARCO, LDL, and LDLR to Disease-Associated Crystalline StructuresFrontiers in immunologyJanuary 1, 2020Alberts A, Klingberg A, Hoffmeister L, Wessig AK, Brand K, Pich A, Neumann K.30 min. We used recombinant human MARCO (R&D Systems, #7586-MA-050), human LDLR (Sino Biological, #10231-H08H-50), human CD32b (Sino Biological, #10259-H08H), and murine LDLR (Sino Biological, #50305-M08H). After

(4) Identification and characterization of highly versatile peptide-vectors that bind non-competitively to the low-density lipoprotein receptor for in vivo targeting and delivery of small molecules and protein cargosPloS oneJanuary 1, 2018David M, Lécorché P, Masse M, Faucon A, Abouzid K, Gaudin N, Varini K, Gassiot F, Ferracci G, Jacquot G, et al.

(5) Optimization and in Vivo Validation of Peptide Vectors Targeting the LDL ReceptorMolecular pharmaceuticsDecember 5, 2016Jacquot G, Lécorché P, Malcor JD, Laurencin M, Smirnova M, Varini K, Malicet C, Gassiot F, Abouzid K, Faucon A, et al.

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Human LDLR / LDL Receptor Protein (His Tag)

Human LDLR / LDL Receptor Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

Citations (5)

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Human LDLR / LDL Receptor Protein (His Tag) from Sino Biological, Inc.

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