Human ACVR2B / ActivinR-IIB Protein (ECD, Fc Tag) 10229-H02H from Sino Biological, Inc.

Product Specs
ItemHuman ACVR2B / ActivinR-IIB Protein (ECD, Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10229-H02H
Activity1. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.02-0.1 µg/mL in the presence of 10 ng/mL recombinant Activin A(Routinely tested). 2. Immobilized Recombinant Human/Mouse/Rat/Cynomolgus/Rhesus Activin A/INHBA Protein (Cat: 10429-HNAH) at 2 µg/mL (100 µl/well) can bind Recombinant Human ACVR2B / ActivinR-IIB Protein (ECD, Fc Tag) (Cat: 10229-H02H), the EC50 is 1.5-4.5 ng/mL (QC tested). 3.Immobilized Recombinant Human/Mouse/Rat/Cynomolgus/Rhesus Activin A/INHBA Protein (Cat: 10429-HNAH) at 5 µg/mL (100 µL/well) can bind Recombinant Human ACVR2B / ActivinR-IIB Protein (ECD, Fc Tag) (Cat: 10229-H02H), the EC50 is 4.6 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg
NCBI Gene AliasesACTRIIB, ActR-IIB, HTX4
NCBI Full Gene Nameactivin A receptor type 2B
Source/Expression SystemHEK293 Cells
Molecule NameACVR2B
SpeciesHuman
Molecular WeightThe recombinant human ACVR2B/Fc chimera is a disulfide-linked homodimer generated after removal of the signal peptide. The reduced monomer comprises 354 amino acids and predicts a molecular mass of 40.0 kDa. As a result of glycosylation, the monomer migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity≥ 97 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Conjugate/TagC-human IgG1-Fc