Mouse ACTRIIB / ACVR2B Protein (His Tag) 50173-M08H from Sino Biological, Inc.

Product Specs
ItemMouse ACTRIIB / ACVR2B Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number50173-M08H
Conjugate/TagC-His
Purity≥ 94 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant mouse ACTRIIB/ACVR2B comprises 127 amino acids and has a predicted molecular mass of 14.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmACVR2B is approximately 33-37 kDa due to glycosylation
SpeciesMouse
Molecule NameACVR2B
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameactivin receptor IIB
NCBI Gene Aliases4930516B21Rik, AI047905, ActRIIB
Activity1. Measured by its binding ability in a functional ELISA. Immobilized Mouse ACVR2B(Cat:50173-M08H) at 2µg/mL (100 µl/well) can bind biotinylated mouse INHBA-His (Cat:50659-M08H), The EC50 of biotinylated mouse INHBA-His (Cat:50659-M08H) is 40-95 ng/mL. 2. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.8 µg/mL in the presence of 10 ng/mL recombinant Activin A. 3.Recombinant Mouse ACVR2B Protein, His Tag (Cat. No. 50173-M08H) immobilized on CM5 chip can bind Recombinant Mouse Activin A Protein, His Tag (Cat. No. 50659-M08H) with an affinity constant of 3.470 nM as determined in an SPR assay (Biacore 8K) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg