Fig 1: Representative SPR Sensorgrams for direct bindings of (A) HDAC4, (B) HDAC5, (C) HDAC7, and (D) HDAC9 to MEF2A. MEF2A was immobilized onto CM5 chips. The continuous colored lines are experimental data and the black dotted lines are fit to the 1:1 kinetics binding model. Each concentration of all class IIa HDACs were injected in duplicate.