Description
FGF10 is comprised of 170aa and is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies have suggested that FGF10 is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. It is also implicated to be a primary factor in the process of wound healing