Description
Introduction: Cholinergic Receptor Nicotinic Alpha 3, also known as CHRNA3 is part of the nicotinic acetylcholine receptor family. Proteins of this family form pentameric complexes comprised of both alpha & beta subunits. Furthermore, CHRNA3 is ligand-gated ions channel which prticipates in neurotransmission. CHRNA3 has been associated with an increased risk of smoking initiation as well as an increased susceptibility to lung cancer.
Description: CHRNA3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (32-240 a.a) and having a molecular mass of 27kDa. CHRNA3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques