Description
M. Tuberculosis remains as the second most cause of death from an infectious diseases in the world. According to WHO report, there were an estimated 8.7 million new cases of TB globally in 2011 and approximately 1.4 million TB-related death. Early and accurate diagnosis of active tuberculosis and differetiation of infection from BCG vaccinated individuals are immediate need in clinical Culture of M. tuberculosis from patients specimen still is gold standard for its diagnosis, but it is expensive and time-consuming. Moex is a new deifined protein from M tuberculosis genome, it is secreted from the infected organ into blood, circulating in blood flow, in kidney, it filtrates through into urine, it is considered as a potential reliable marker for M. tuberculosis diagnosis with convenience for urine test, urine test is convenient and time saving test, suitable to screen large population. It was also found reactive to the specific antibody induced by M tuberculosis organism, it can be used as a useful antigen to detect the specific antibody for the clinical diagnosis of M. tuberculosis infection. rMoeX protein is a 38kDa with a 6 x his tag attached at its C-terminus. It is soluble in phosphate buffer