Recombinant Human CCL21/6Ckine Protein, CF 366-6C-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human CCL21/6Ckine Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $415.00Supplier Page View Company Product Page
Catalog Number366-6C-025/CF
SpeciesHuman
Molecule NameCCL21/6Ckine
Size25 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 16-17 kDa, reducing conditions
Theoretical: 12 kDa
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human CCL21/6Ckine Protein, CF
NCBI Full Gene NameC-C motif chemokine ligand 21
NCBI Gene Aliases6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfationCell Chemical BiologyAugust 1, 2023Christoffer K. Goth, Akul Y. Mehta, Alyssa M. McQuillan, Kelly J. Baker, Melinda S. Hanes, Simon S. Park, Kathrin Stavenhagen, Gertrud M. Hjortø, Jamie Heimburg-Molinaro, Elliot L. Chaikof, et al.Systems,CCL5-50ug278-RN-050/CF CCL7,Chemotactics,CCL7-50ug CCL14,Chemotactics,CCL14-50ug CCL27,Chemotactics,CCL27-50ug CCL28,Chemotactics,CCL28-50ug CXCL8,Chemotactics,CXCL8-50ug CXCL10,Chemotactics,CXCL10-50ug CXCL12,Chemotactics,CXCL12-50ug CCL19,R&D SystemsChemotactics,361-MI-025/CFCCL19-50ug CCL21,R&D Systems,366-6C-025/CF Critical Commercial Assays,Critical Commercial Assays,Critical Commercial Assays CellTiter glo,Promega,G7570 Deposited

(2) Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding functionPloS oneJanuary 1, 2023Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, Powers M, Wang J, Dower C, Hegen M, et al.

(3) Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic TailsInternational journal of molecular sciencesJanuary 26, 2022Brandum EP, Jørgensen AS, Calvo MB, Spiess K, Peterson FC, Yang Z, Volkman BF, Veldkamp CT, Rosenkilde MM, Goth CK, et al.

(4) CXCL12-stimulated lymphocytes produce secondary stimulants that affect the surrounding cell chemotaxisBiochemistry and biophysics reportsDecember 1, 2021Kurowarabe K, Endo M, Kobayashi D, Hayasaka H.

(5) RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapyeLifeOctober 27, 2021Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanářová O, Radaszkiewicz KA, Picková M, Víchová R, Gybeľ T, Kaiser K, Demková L, et al.

(6) Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4⁺, CD8⁺ T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancerCancer cell internationalSeptember 7, 2021Dhandapani H, Jayakumar H, Seetharaman A, Singh SS, Ganeshrajah S, Jagadish N, Suri A, Thangarajan R, Ramanathan P.

(7) Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive DefenseCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Mao FY, Lv YP, Hao CJ, Teng YS, Liu YG, Cheng P, Yang SM, Chen W, Liu T, Zou QM, et al.

(8) A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel diseasePloS oneJanuary 1, 2021Capitano ML, Jaiswal A, Broxmeyer HE, Pride Y, Glover S, Amlashi FG, Kirby A, Srinivasan G, Williamson EA, Mais D, et al.

(9) A mutation that blocks integrin α₄β₇ activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitisBMC biologyJune 10, 2020Zhang H, Zheng Y, Pan Y, Lin C, Wang S, Yan Z, Lu L, Ge G, Li J, Zeng YA, et al.

(10) The lymph node stromal laminin α5 shapes alloimmunityThe Journal of clinical investigationMay 1, 2020Li L, Shirkey MW, Zhang T, Xiong Y, Piao W, Saxena V, Paluskievicz C, Lee Y, Toney N, Cerel BM, et al.

(11) Resident memory T cells are a cellular reservoir for HIV in the cervical mucosaNature communicationsOctober 18, 2019Cantero-Pérez J, Grau-Expósito J, Serra-Peinado C, Rosero DA, Luque-Ballesteros L, Astorga-Gamaza A, Castellví J, Sanhueza T, Tapia G, Lloveras B, et al.

(12) The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathwayCell death & diseaseJuly 1, 2019Ye Z, Zhong L, Zhu S, Wang Y, Zheng J, Wang S, Zhang J, Huang R.

(13) A CD4⁺ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinateNature medicineJanuary 1, 2019Caielli S, Veiga DT, Balasubramanian P, Athale S, Domic B, Murat E, Banchereau R, Xu Z, Chandra M, Chung CH, et al.

(14) Dendritic cells pulsed with generated tumor cell lysate from Phyllanthus amarus Schum. & Thonn. induces anti-tumor immune responseBMC complementary and alternative medicineAugust 6, 2018Mohamed SIA, Jantan I, Nafiah MA, Seyed MA, Chan KM.

(15) Regulation of CCR7-dependent cell migration through CCR7 homodimer formationScientific reportsAugust 17, 2017Kobayashi D, Endo M, Ochi H, Hojo H, Miyasaka M, Hayasaka H.

(16) Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical UseJournal of immunology researchJanuary 1, 2017Van den Bergh JMJ, Smits ELJM, Versteven M, De Reu H, Berneman ZN, Van Tendeloo VFI, Lion E.

(17) Progesterone Levels Associate with a Novel Population of CCR5+CD38+ CD4 T Cells Resident in the Genital Mucosa with Lymphoid Trafficking PotentialJournal of immunology (Baltimore, Md. : 1950)July 1, 2016Swaims-Kohlmeier A, Haaland RE, Haddad LB, Sheth AN, Evans-Strickfaden T, Lupo LD, Cordes S, Aguirre AJ, Lupoli KA, Chen CY, et al.

(18) Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cellsJournal of immunology (Baltimore, Md. : 1950)March 1, 2015Till KJ, Pettitt AR, Slupsky JR.

(19) The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesisMolecular cancerFebruary 10, 2015Tutunea-Fatan E, Majumder M, Xin X, Lala PK.

(20) Preferential recruitment of Th17 cells to cervical cancer via CCR6-CCL20 pathwayPloS oneJanuary 1, 2015Yu Q, Lou XM, He Y.

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Recombinant Human CCL21/6Ckine Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human CCL21/6Ckine Protein, CF from R&D Systems, a Bio-Techne Brand

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