Recombinant Mouse Cathepsin B Protein, CF 965-CY-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse Cathepsin B Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number965-CY-010
SpeciesMouse
Molecule NameCathepsin B
Size10 ug
FormatSupplied as a 0.2 µm filtered solution in Tris and NaCl
NCBI Full Gene Namecathepsin B
NCBI Gene AliasesCB
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 43 kDa, reducing conditions
Theoretical: 37 kDa
ApplicationsEnzyme Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse Cathepsin B Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interceptionbioRxiv : the preprint server for biologyJuly 2, 2025Wang CS, Zhong Q, Wang ST, Martin-Alonso C, Neaher S, Patel S, Parisi T, Kirkpatrick JD, Sequist LV, Jacks TE, et al.

(2) Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH RangeBiochemistryAugust 1, 2023Yoon MC, Phan V, Podvin S, Mosier C, O'Donoghue AJ, Hook V.#1080-CY-010), and procathepsin X (R&D, #934-CY). Mouse cathepsin B was obtained from R&D Systems (R&D Systems, #965-CY-010). The UniProt identification numbers for the human cathepsin proteases studied are P07858 for cathepsin

(3) Tumor-Specific Monomethyl Auristatin E (MMAE) Prodrug Nanoparticles for Safe and Effective ChemotherapyPharmaceuticsOctober 7, 2022Cho H, Shim MK, Moon Y, Song S, Kim J, Choi J, Kim J, Lee Y, Park JY, Kim Y, et al.

(4) Crosstalk between dihydroceramides produced by Porphyromonas gingivalis and host lysosomal cathepsin B in the promotion of osteoclastogenesisJournal of cellular and molecular medicineMay 1, 2022Duarte C, Yamada C, Garcia C, Akkaoui J, Ho A, Nichols F, Movila A.

(5) Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin BScientific reportsJune 24, 2019Demcsák A, Geisz A, Sahin-Tóth M.

(6) Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon OutgrowthThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 6, 2018Tran AP, Sundar S, Yu M, Lang BT, Silver J.

(7) Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primatesNature biotechnologyMarch 1, 2016Vegas AJ, Veiseh O, Doloff JC, Ma M, Tam HH, Bratlie K, Li J, Bader AR, Langan E, Olejnik K, et al.quantification. In vitro cathepsin activity assay Recombinant Mouse Cathepsin B (rmCathepsin B, R&D system, 965-CY-010) was diluted to 10 µM in Activation Buffer (25 mM MES, 5 mM DTT, pH 5.0), incubated at room temperature

(8) Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinaseJournal of immunology (Baltimore, Md. : 1950)June 15, 2014McComb S, Shutinoski B, Thurston S, Cessford E, Kumar K, Sad S.

(9) Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growthNature medicineJanuary 1, 2013Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, et al.

(10) VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formationCancer researchMay 15, 2009Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, et al.

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Recombinant Mouse Cathepsin B Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse Cathepsin B Protein, CF from R&D Systems, a Bio-Techne Brand

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