Recombinant Mouse CCL21/6Ckine Protein, CF 457-6C-025/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse CCL21/6Ckine Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $449.00Supplier Page View Company Product Page
Catalog Number457-6C-025/CF
SpeciesMouse
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA
Molecule NameCCL21/6Ckine
Size25 ug
NCBI Full Gene Namechemokine (C-C motif) ligand 21A (serine)
NCBI Gene Aliasesplt, Scya21b, SLC, SCYA21a, Scya21, CKb9, 6Ckine, Tca4, Gm1987, ALP, 6CKBAC2
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 16-17 kDa, reducing conditions
Theoretical: 12 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse CCL21/6Ckine Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

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(2) Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding functionPloS oneJanuary 1, 2023Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, Powers M, Wang J, Dower C, Hegen M, et al.

(3) Malnutrition-related parasite dissemination from the skin in visceral leishmaniasis is driven by PGE2-mediated amplification of CCR7-related trafficking of infected inflammatory monocytesPLoS neglected tropical diseasesJanuary 1, 2023Osorio EY, Uscanga-Palomeque A, Patterson GT, Cordova E, Travi BL, Soong L, Melby PC.

(4) A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteriaNature MicrobiologyAugust 18, 2022Lina Yao, Gabriel D. D’Agostino, Jinseok Park, Saiyu Hang, Arijit A. Adhikari, Yancong Zhang, Wei Li, Julian Avila-Pacheco, Sena Bae, Clary B. Clish, et al.plated onto the upper chamber of Transwells (Corning, Cat. 3421). CCL21 (200ng/ml, R&D Systems, Cat. 457–6C-025/CF) was added to the bottom chamber. After incubation at 37 °C for 6 h, cells migrated to the bottom chamber

(5) GPR174 signals via Gαs to control a CD86-containing gene expression program in B cellsProceedings of the National Academy of Sciences of the United States of AmericaJune 7, 2022Wolf EW, Howard ZP, Duan L, Tam H, Xu Y, Cyster JG.

(6) PD-L1 signaling selectively regulates T cell lymphatic transendothelial migrationNature communicationsApril 21, 2022Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, Lape IT, Paluskievicz C, Hippen KL, Lee Y, et al.

(7) Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusionNatureNovember 1, 2021Sun X, Wu B, Chiang HC, Deng H, Zhang X, Xiong W, Liu J, Rozeboom AM, Harris BT, Blommaert E, et al.allowed to migrate at 37 °C for 2 h in the presence of recombinant CCL21 (100 ng ml−1, R&D systems, 4576C025CF), either with decellularized ECM pre-seeded in the inserts or with tumour-conditioned medium in the

(8) The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin IINature communicationsJune 7, 2021Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, Konaka H, Morita T, Kato Y, Nishide M, et al.

(9) Expression of leukotriene B₄ receptor 1 defines functionally distinct DCs that control allergic skin inflammationCellular & molecular immunologyJune 1, 2021Koga T, Sasaki F, Saeki K, Tsuchiya S, Okuno T, Ohba M, Ichiki T, Iwamoto S, Uzawa H, Kitajima K, et al.

(10) Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive DefenseCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Mao FY, Lv YP, Hao CJ, Teng YS, Liu YG, Cheng P, Yang SM, Chen W, Liu T, Zou QM, et al.

(11) T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal InflammationCell reportsJune 30, 2020Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C.

(12) A mutation that blocks integrin α₄β₇ activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitisBMC biologyJune 10, 2020Zhang H, Zheng Y, Pan Y, Lin C, Wang S, Yan Z, Lu L, Ge G, Li J, Zeng YA, et al.

(13) Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell ResponseCancersMay 19, 2020Trempolec N, Degavre C, Doix B, Brusa D, Corbet C, Feron O.

(14) The lymph node stromal laminin α5 shapes alloimmunityThe Journal of clinical investigationMay 1, 2020Li L, Shirkey MW, Zhang T, Xiong Y, Piao W, Saxena V, Paluskievicz C, Lee Y, Toney N, Cerel BM, et al.

(15) Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal MesotheliomaCancersFebruary 27, 2020Trempolec N, Doix B, Degavre C, Brusa D, Bouzin C, Riant O, Feron O.

(16) Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signalingThe Journal of clinical investigationMay 20, 2019Capitano ML, Mor-Vaknin N, Saha AK, Cooper S, Legendre M, Guo H, Contreras-Galindo R, Kappes F, Sartor MA, Lee CT, et al.

(17) Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand SpecificityFrontiers in microbiologyJanuary 1, 2019Sharif S, Ueda N, Nakatani Y, Wise LM, Clifton S, Lateef Z, Mercer AA, Fleming SB.

(18) Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic ReprogrammingCell reportsDecember 11, 2018Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, Tregnago C, Corrado M, Pigazzi M, Barnaba V, et al.,Sigma Aldrich,A6003-100G CXCL12,R&D System,460-SD-010/CF CCL19,R&D System,440-M3-025/CF CCL21,R&D System,457-6C-025/CF Spinghosine-1-phosphate,Tocris,1370 mdivi-1,Sigma Aldrich,M1099-25MG oligomycin,Sigma Aldrich,75351-5MG formaldehyde

(19) Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymuseLifeSeptember 6, 2018Moretti FA, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, Scheiermann C, Sperandio M, Fässler R, Moser M.

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Recombinant Mouse CCL21/6Ckine Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse CCL21/6Ckine Protein, CF from R&D Systems, a Bio-Techne Brand

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