Recombinant Human CNTF Protein, CF 257-NT-010/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human CNTF Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $257.00Supplier Page View Company Product Page
Catalog Number257-NT-010/CF
SpeciesHuman
Size10 ug (also 50 ug)
Molecule NameCNTF
FormatLyophilized from a 0.2 µm filtered solution in Tris, NaCl, TCEP, EDTA, CHAPS and Trehalose
NCBI Full Gene Nameciliary neurotrophic factor
NCBI Gene AliasesHCNTF
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 23-26 kDa, reducing conditions
Theoretical: 22.8 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Human CNTF Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, 2 to 8 °C under sterile conditions after reconstitution

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(2) Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell statesbioRxiv : the preprint server for biologyJune 5, 2023Gazestani V, Kamath T, Nadaf NM, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Rauramaa T, Therrien M, Tegtmeyer M, et al.

(3) A Potent and Selective CDKL5/GSK3 Chemical Probe is NeuroprotectivebioRxiv : the preprint server for biologyFebruary 10, 2023Ong HW, Liang Y, Richardson W, Lowry ER, Wells CI, Chen X, Silvestre M, Dempster K, Silvaroli JA, Smith JL, et al.

(4) Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neuronsCell stem cellFebruary 2, 2023Álvarez Z, Ortega JA, Sato K, Sasselli IR, Kolberg-Edelbrock AN, Qiu R, Marshall KA, Nguyen TP, Smith CS, Quinlan KA, et al.

(5) SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALSCell stem cellFebruary 2, 2023Linares GR, Li Y, Chang WH, Rubin-Sigler J, Mendonca S, Hong S, Eoh Y, Guo W, Huang YH, Chang J, et al.

(6) Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neuronsCell reportsJanuary 31, 2023Pietiläinen O, Trehan A, Meyer D, Mitchell J, Tegtmeyer M, Valakh V, Gebre H, Chen T, Vartiainen E, Farhi SL, et al.

(7) CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive statesNature neuroscienceNovember 1, 2022Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, et al.

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(11) Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial CellsInternational journal of molecular sciencesJanuary 27, 2022Lindkvist M, Zegeye MM, Grenegård M, Ljungberg LU.

(13) Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1PloS oneJanuary 1, 2022Eltahir MK, Nakamori M, Hattori S, Kimura T, Mochizuki H, Nagano S.neurotrophic factor (GDNF) (Cat# 212-GD/CF, R&D Systems), ciliary neurotrophic factor (CNTF) (Cat# 257-NT-010/CF, R&D Systems) and neurotrophin-3 (NT-3) (Cat# 267-N3/CF, R&D Systems) and medium was changed every 4

(14) Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic miceMolecular therapy. Nucleic acidsDecember 3, 2021Ge Y, Zhang R, Feng Y, Lu J, Li H.neurotrophic factor (248-BDB-050/CF; R&D Systems, Minneapolis, MN), 10 ng/mL ciliary neurotrophic factor (257-NT-010/CF; R&D Systems), 10 ng/mL forskolin (1099/10; R&D Systems), and 10 ng/mL basic fibroblast growth factor

(15) A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translationNature communicationsOctober 15, 2021Sonobe Y, Aburas J, Krishnan G, Fleming AC, Ghadge G, Islam P, Warren EC, Gu Y, Kankel MW, Brown AEX, et al.

(18) Arginine vasopressin-Venus reporter mice as a tool for studying magnocellular arginine vasopressin neuronsPeptidesMay 1, 2021Hagiwara D, Tochiya M, Azuma Y, Tsumura T, Hodai Y, Kawaguchi Y, Miyata T, Kobayashi T, Sugiyama M, Onoue T, et al.

(19) TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respirationCell reportsMarch 23, 2021Russ K, Teku G, Bousset L, Redeker V, Piel S, Savchenko E, Pomeshchik Y, Savistchenko J, Stummann TC, Azevedo C, et al.

(20) Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiationBMC molecular and cell biologyFebruary 18, 2021Solomon E, Davis-Anderson K, Hovde B, Micheva-Viteva S, Harris JF, Twary S, Iyer R.

Recombinant Human CNTF Protein, CF