Recombinant Human Frizzled-5 Fc Chimera Protein, CF 1617-FZ-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Frizzled-5 Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number1617-FZ-050
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameFrizzled-5
Size50 ug
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 55-60 kDa, reducing conditions
Theoretical: 42.5 kDa (monomer)
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Frizzled-5 Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namefrizzled class receptor 5
NCBI Gene AliasesC2orf31, HFZ5

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(1) A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathyEMBO molecular medicineJuly 7, 2021Chidiac R, Abedin M, Macleod G, Yang A, Thibeault PE, Blazer LL, Adams JJ, Zhang L, Roehrich H, Jo HN, et al.

(2) Wnt-5a/Frizzled9 Receptor Signaling through the Gαo-Gβγ Complex Regulates Dendritic Spine FormationThe Journal of biological chemistrySeptember 2, 2016Ramírez VT, Ramos-Fernández E, Henríquez JP, Lorenzo A, Inestrosa NC.

(3) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(4) Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signalingThe Journal of biological chemistryApril 4, 2008Magdesian MH, Carvalho MM, Mendes FA, Saraiva LM, Juliano MA, Juliano L, Garcia-Abreu J, Ferreira ST.

Recombinant Human Frizzled-5 Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand