Recombinant Mouse IL-1 RI Fc Chimera Protein, CF 771-MR-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse IL-1 RI Fc Chimera Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $567.00Supplier Page View Company Product Page
Catalog Number771-MR-100
SpeciesMouse
Size100 ug
Molecule NameIL-1 RI
FormatLyophilized from a 0.2 µm filtered solution in PBS
NCBI Full Gene Nameinterleukin 1 receptor, type I
NCBI Gene AliasesIl1r-1, CD121a, CD121b, IL-iR, IL-1R1, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1
Purity>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 95-110 kDa, reducing conditions
Theoretical: 63.8 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse IL-1 RI Fc Chimera Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) CNS-targeted NLRP3 Inhibition by NT-0527 confers therapeutic advantage in a CAPS mouse modelJournal of NeuroinflammationFebruary 21, 2026Beverly H. Koller, MyTrang Nguyen, John R. Doedens, David Harrison, Nicholas Clarke, Alan P. Watt, Christopher A. Gabeltotal volume was adjusted to 0.5 mL with homogenization buffer, and 2 µg of mIL-1R1-Fc (R&D Systems, #771-MR-100; 20 µL of a 100 µg/mL stock prepared in sterile PBS) were added. The resulting solutions were mixed

(2) Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational FrameworkACS pharmacology & translational scienceMay 10, 2024Doedens JR, Smolak P, Nguyen M, Wescott H, Diamond C, Schooley K, Billinton A, Harrison D, Koller BH, Watt AP, et al.human IL-1β (Novus; NBC1–18478), mouse IL-1β (R&D Systems; 401-ML), and murine IL-1R-Fc (R&D Systems; 771-MR-100). ELISA kits employed to measure cytokines within in vivo derived samples were obtained from ThermoFisher

(3) Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat dietEndocrinologyApril 1, 2010Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL.

(4) IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complexJournal of immunology (Baltimore, Md. : 1950)August 15, 2007Chackerian AA, Oldham ER, Murphy EE, Schmitz J, Pflanz S, Kastelein RA.

(5) Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3Journal of immunology (Baltimore, Md. : 1950)June 1, 2007O'Connor JC, Sherry CL, Guest CB, Freund GG.

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Recombinant Mouse IL-1 RI Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse IL-1 RI Fc Chimera Protein, CF from R&D Systems, a Bio-Techne Brand

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