Recombinant Rat Leptin Protein, CF 598-LP-01M from R&D Systems, a Bio-Techne Brand | Biocompare.com

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R&D Systems, a Bio-Techne Brand for
Recombinant Rat Leptin Protein, CF

Product Specs
ItemRecombinant Rat Leptin Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $261.00Supplier Page View Company Product Page
Catalog Number598-LP-01M
SpeciesRat
Source/Expression SystemE. coli-derived Recombinant Rat Leptin Protein, CF
Size1 mg (also 5 mg)
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameLeptin/OB
NCBI Full Gene Nameleptin
NCBI Gene Aliasesobese, OB
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular Weight16.2 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Effect of C-reactive protein deficiency on insulin resistance reversal in rats with polycystic ovary syndrome through augmented leptin actionDiabetology & metabolic syndromeSeptember 2, 2023Li K, Hu L, Li X, Yuan Z, He J, Liu D, Yang G, Yuan L.

(2) The Acute Effects of Leptin on the Contractility of Isolated Rat Atrial and Ventricular CardiomyocytesInternational journal of molecular sciencesJuly 28, 2022Khokhlova A, Myachina T, Butova X, Kochurova A, Polyakova E, Galagudza M, Solovyova O, Kopylova G, Shchepkin D.

(3) Hyperleptinemia results in systemic inflammation and the exacerbation of ischemia-reperfusion myocardial injuryHeliyonNovember 1, 2021Polyakova EA, Mikhaylov EN, Galagudza MM, Shlyakhto EV.

(4) Modulation of Sirt1 and FoxO1 on Hypothalamic Leptin-Mediated Sympathetic Activation and Inflammation in Diet-Induced Obese RatsJournal of the American Heart AssociationJuly 20, 2021Liu X, Zheng H.

(5) Roux-en-Y gastric bypass contributes to weight loss-independent improvement in hypothalamic inflammation and leptin sensitivity through gut-microglia-neuron-crosstalkMolecular metabolismJune 1, 2021Chen J, Haase N, Haange SB, Sucher R, Münzker J, Jäger E, Schischke K, Seyfried F, von Bergen M, Hankir MK, et al.

(6) Responsiveness of hypothalamo-pituitary-adrenal axis to leptin is impaired in diet-induced obese ratsNutrition & diabetesMarch 18, 2019Shin AC, MohanKumar SMJ, Balasubramanian P, Sirivelu MP, Linning K, Woolcock A, James M, MohanKumar PS.

(7) Development of leptin resistance in sucrose drinking rats is associated with consuming carbohydrate-containing solutions and not calorie-free sweet solutionAppetiteJanuary 1, 2019Harris RBS.

(8) Leptin Aggravates Reflux Esophagitis by Increasing Tissue Levels of Macrophage Migration Inhibitory Factor in RatsThe Tohoku journal of experimental medicineMay 1, 2018Murata T, Asanuma K, Ara N, Iijima K, Hatta W, Hamada S, Asano N, Koike T, Imatani A, Masamune A, et al.

(9) Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK-ERK signalling pathway in vivo and in vitroJournal of cellular and molecular medicineApril 1, 2018Han YC, Ma B, Guo S, Yang M, Li LJ, Wang SJ, Tan J.

(10) Leptin enhances hypothalamic lactate dehydrogenase A (LDHA)-dependent glucose sensing to lower glucose production in high-fat-fed ratsThe Journal of biological chemistryMarch 16, 2018Abraham MA, Rasti M, Bauer PV, Lam TKT.

(11) Leptin-induced basal Akt phosphorylation and its implication in exercise-mediated improvement of insulin sensitivityBiochemical and biophysical research communicationsJanuary 29, 2018Zheng X, Niu S.

(12) Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley ratPloS oneJanuary 1, 2017Vargas VE, Gurung S, Grant B, Hyatt K, Singleton K, Myers SM, Saunders D, Njoku C, Towner R, Myers DA.

(13) Fourth-ventricle leptin infusions dose-dependently activate hypothalamic signal transducer and activator of transcription 3American journal of physiology. Endocrinology and metabolismDecember 1, 2016Harris RB, Desai BN.

(14) Leptin Attenuates the Contractile Function of Adult Rat Cardiomyocytes Involved in Oxidative Stress and AutophagyActa Cardiologica SinicaNovember 1, 2016Luo LJ, Liu YP, Yuan X, Zhang GP, Hou N, Wu XQ, Luo JD, Zhang GS.

(15) Renal hemodynamic and morphological changes after 7 and 28 days of leptin treatment: the participation of angiotensin II via the AT1 receptorPloS oneJanuary 1, 2015Thieme K, Oliveira-Souza M.

(16) Blockade of the cerebral aqueduct in rats provides evidence of antagonistic leptin responses in the forebrain and hindbrainAmerican journal of physiology. Endocrinology and metabolismFebruary 15, 2014Vaill MI, Desai BN, Harris RB.

(17) Leptin-induced endothelium-dependent vasorelaxation of peripheral arteries in lean and obese rats: role of nitric oxide and hydrogen sulfidePloS oneJanuary 1, 2014Jamroz-Wiśniewska A, Gertler A, Solomon G, Wood ME, Whiteman M, Bełtowski J.

(18) Leptin augments the acute suppressive effects of insulin on hepatic very low-density lipoprotein production in ratsEndocrinologyMay 1, 2009Huang W, Metlakunta A, Dedousis N, Ortmeyer HK, Stefanovic-Racic M, O'Doherty RM.

(19) Leptin increases adult hippocampal neurogenesis in vivo and in vitroThe Journal of biological chemistryJune 27, 2008Garza JC, Guo M, Zhang W, Lu XY.

(20) Leptin modulates the response to oleic acid in the pharynxNeuroscience lettersAugust 16, 2007Kitagawa J, Shingai T, Kajii Y, Takahashi Y, Taguchi Y, Matsumoto S.

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