Recombinant Human Fc gamma RIIIB/CD16b Protein, CF 1597-FC-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Fc gamma RIIIB/CD16b Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $465.00Supplier Page View Company Product Page
Catalog Number1597-FC-050/CF
SpeciesHuman
Size50 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameFc gamma RIIIB/CD16b
NCBI Full Gene NameFc gamma receptor IIIb
NCBI Gene AliasesFCRIIIb, FCR-10, FCGR3, FCRIII, FCG3, FCGR3A, CD16, CD16A, CD16b, CD16-I
Molecular WeightObserved: 40-60 kDa, reducing conditions
Theoretical: 22.7 kDa
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Fc gamma RIIIB/CD16b Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Discovery of a novel Igβ and FcγRIIB cross-linking antibody, ASP2713, and its potential application in the treatment of systemic lupus erythematosusInternational immunopharmacologyDecember 1, 2021Kitanaga Y, Yamajuku D, Kubo S, Nakamura K, Maeda M, Seki M, Kaneko Y, Kinugasa F, Morokata T, Kondo Y, et al.

(2) Potent Cytolytic Activity and Specific IL15 Delivery in a Second-Generation Trispecific Killer EngagerCancer Immunology ResearchSeptember 1, 2020Martin Felices et al.CD16b. The ligands, rhCD16A or rhCD16B with a c-terminal 6x-HIS tag (R&D Systems cat#: 4325-FC-050 and 1597-FC-050/CF, respectively) were captured on biosensor tips using His tag-specific dip and read biosensors. The biosensor

(3) Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related PeptideJournal of Pharmacology and Experimental TherapeuticsJuly 1, 2020Leon F. Garcia-Martinez et al.FcgRIIB/C (CD32b/c), cat. no. 1875-CD-050; FcgRIIIA/ CD16a, cat. no. 4325-FC-050; FcgRIIIB/CD16b, cat. no. 1597-fc-050/ CF; R&D Systems, Minneapolis, MN] were diluted to 7 mg/ml in 20 mM sodium acetate pH 5.5 and coupled to

(4) Insertion of N-Terminal Hinge Glycosylation Enhances Interactions of the Fc Region of Human IgG1 Monomers with Glycan-Dependent Receptors and Blocks Hemagglutination by the Influenza VirusJournal of immunology (Baltimore, Md. : 1950)March 1, 2019Blundell PA, Lu D, Wilkinson M, Dell A, Haslam S, Pleass RJ.

(5) Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumabmAbsMay 1, 2018Seo N, Polozova A, Zhang M, Yates Z, Cao S, Li H, Kuhns S, Maher G, McBride HJ, Liu J.

(6) Stabilizing the C_H2 Domain of an Antibody by Engineering in an Enhanced Aromatic SequonACS Chemical BiologyJuly 15, 2016Wentao Chen, Leopold Kong, Stephen Connelly, Julia M. Dendle, Yu Liu, Ian A. Wilson, Evan T. Powers, Jeffery W. Kellyreceptors. Recombinant Fc gamma receptors were from R&D Systems (Cat. No. 1257FC050, 1330CD050CF, 4325FC050, 1597FC050CF). Recombinant FcRn was from Novoprotein (Cat. No. 50828338). All binding data were collected at 25°C.

(7) Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseasesJournal of immunology (Baltimore, Md. : 1950)May 1, 2014Xie JH, Yamniuk AP, Borowski V, Kuhn R, Susulic V, Rex-Rabe S, Yang X, Zhou X, Zhang Y, Gillooly K, et al.

(8) Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicitymAbsMarch 1, 2014Derer S, Glorius P, Schlaeth M, Lohse S, Klausz K, Muchhal U, Desjarlais JR, Humpe A, Valerius T, Peipp M.

(9) Bi-specific aptamers mediating tumor cell lysisThe Journal of biological chemistryJune 17, 2011Boltz A, Piater B, Toleikis L, Guenther R, Kolmar H, Hock B.

(10) α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8The Journal of clinical investigationDecember 1, 2010Bergin DA, Reeves EP, Meleady P, Henry M, McElvaney OJ, Carroll TP, Condron C, Chotirmall SH, Clynes M, O'Neill SJ, et al.

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Fc gamma RIIIB/CD16b Protein

Fc gamma RIIIB/CD16b Protein

Fc gamma RIIIB/CD16b Protein

Fc gamma RIIIB/CD16b Protein

Recombinant Human Fc gamma RIIIB/CD16b Protein, CF from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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Recombinant Human Fc gamma RIIIB/CD16b Protein, CF from R&D Systems, a Bio-Techne Brand

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